Reaction state_transition ce_re158
FANCD2|pho@Nucleus
→ FANCD2|K561_ubi|pho@Nucleus
Reaction regulators:
- Boolean_logic_gate_and
- BLM:FAAP100*:FAAP20*:FAAP24*:FANCA|pho:FANCB:FANCC:FANCE|S376_pho|T346_pho:FANCF:FANCG|S7_pho:FANCL:FANCM:HES1@Nucleus
and UBE2T@Nucleus
- Catalysis
- UBE2T@Nucleus
- BLM:FAAP100*:FAAP20*:FAAP24*:FANCA|pho:FANCB:FANCC:FANCE|S376_pho|T346_pho:FANCF:FANCG|S7_pho:FANCL:FANCM:HES1@Nucleus
- Modulation
- G1 phase@Nucleus
References
S phase checkpoint controls and induces FANCD2 monoubiquitusation to start Fanconi and HR
PMID:12239151