Protein HUS1 map

Identifiers
HUS1 checkpoint homolog (S. pombe)
HUGO:HUS1, HGNC:5309, ENTREZ:3364, UNIPROT:O60921

Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
 Cell Cycle DNA Repair  map  / S_PHASE_CHECKPOINT  map

References
PMID:15459660, PMID:9524127, PMID:17493829

Modifications:
In compartment: Nucleus
  1. HUS1@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. HUS1:​RAD1:​RAD9*|​pho@Nucleus map
  2. HUS1:​RAD1:​RAD9*|​pho:​TDG@Nucleus map
  3. HUS1:​MUTH*:​RAD1:​RAD9*|​pho@Nucleus map
  4. HUS1:​NEIL1:​RAD1:​RAD9*|​pho@Nucleus map
  5. HUS1:​RAD1:​RAD17:​RAD9*:​RFC*@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. RAD1@Nucleus map + RAD9*|​pho@Nucleus map + HUS1@Nucleus map → map HUS1:​RAD1:​RAD9*|​pho@Nucleus map
  2. HUS1:​RAD1:​RAD9*|​pho@Nucleus map + RAD17@Nucleus map + RFC*@Nucleus map → map HUS1:​RAD1:​RAD17:​RAD9*:​RFC*@Nucleus map
  3. NEIL1@Nucleus map + HUS1:​RAD1:​RAD9*|​pho@Nucleus map → map HUS1:​NEIL1:​RAD1:​RAD9*|​pho@Nucleus map
  4. HUS1:​MUTH*:​RAD1:​RAD9*|​pho@Nucleus map + HUS1:​RAD1:​RAD9*|​pho@Nucleus map + MUTH*@Nucleus map → map HUS1:​MUTH*:​RAD1:​RAD9*|​pho@Nucleus map
  5. TDG@Nucleus map + HUS1:​RAD1:​RAD9*|​pho@Nucleus map → map HUS1:​RAD1:​RAD9*|​pho:​TDG@Nucleus map
As Catalyser:
  1. gBER_M-glyc_DNA_st2*@Nucleus map → map gBER_M-glyc_DNA_st3*@Nucleus map
  2. S phase@Nucleus map → map G2 phase@Nucleus map
  3. gLnP_BER_M-glyc_st5*@Nucleus map → map gLnP_BER_M-glyc_st6*@Nucleus map
  4. ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*@Nucleus map + MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7@Nucleus map + CDT1@Nucleus map + CDC6@Nucleus map + CDC45@Nucleus map + POLA*@Nucleus map + PRIM*@Nucleus map + RPA1@Nucleus map + RPA2@Nucleus map + RPA3@Nucleus map → map CDC45:​CDC6:​CDT1:​MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7:​ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*:​POLA*:​PRIM*@Nucleus map
  5. CDC7@Nucleus map + DBF4@Nucleus map → map CDC7:​DBF4@Nucleus map
  6. gBER_M-glyc_DNA_st3*@Nucleus map + dNTPs@Nucleus map → map gLnP_BER_M-glyc_st4*@Nucleus map
  7. ATRIP:​ATR|​pho:​CLSPN|​pho@Nucleus map + TIPIN@Nucleus map + TIM1*@Nucleus map + CHEK1|​pho|​active@Nucleus map → map ATRIP:​ATR|​pho:​CHEK1|​pho:​CLSPN|​pho:​TIM1*:​TIPIN@Nucleus map
  8. gDeaminated_alkylated_mismatched_base*@Nucleus map → map gBER_M-glyc_DNA_st2*@Nucleus map + Base@Nucleus map
  9. gOxidized_ring-saturated_hydrolysed_base*@Nucleus map → map gBER_B-glyc_DNA_st2*@Nucleus map + Base@Nucleus map
  10. gLnP_BER_M-glyc_st4*@Nucleus map → map gLnP_BER_M-glyc_st5*@Nucleus map + Modified 2-12 nucl fragment@Nucleus map