Protein PYGO* map

Identifiers
pygopus homolog 1 (Drosophila)
HUGO:PYGO1 HGNC:30256 ENTREZ:26108 UNIPROT:Q9Y3Y4 GENECARDS:PYGO1 WIKI:PYGO1

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map

PYGO*@Nucleus

References
s_wca3_re3( Survival  map ):
Upon wnt signalling beta-catenin is not degraded and can enter the nucleus
BCL9 and PYGO stimulate translocation of b-catenin.
PMID:15208637
No active transport of b-catenin localisation of b-catenin by retention of the binding partners
PMID:16554443

Modifications:
In compartment: Nucleus
  1. PYGO*@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. BCL9:​PYGO*:​_beta_-Catenin*|​ace@Nucleus map
  2. BCL9:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map
  3. BCL9:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map
  4. BCL9:​CBP*|​S92_pho:​PYGO*:​_beta_-Catenin*|​ace|​ace@Nucleus map
  5. BCL9:​KLF8|​K67_ace|​K93_ace|​K95_ace:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map
  6. BCL9:​PYGO*:​SMAD1|​pho:​TCF4:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map
  7. BCL9:​DVL*:​JUN|​pho|​pho:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map
  8. BCL9:​CTBP*:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​ace@Nucleus map
  9. BCL9:​CBP*|​S92_pho:​DVL*:​JUN|​pho|​pho:​PYGO*:​_beta_-Catenin*|​ace|​ace@Nucleus map
  10. BCL9:​KLF8|​K67_ace|​K93_ace|​K95_ace:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map
  11. BCL9:​DVL*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map
  12. BCL9:​CBP*|​S92_pho:​DVL*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_emp|​ace|​ace@Nucleus map
  13. APC|​T1487_pho:​BCL9:​CTBP*|​hm2:​DVL*:​HDAC1_2*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. BCL9:​PYGO*:​_beta_-Catenin*|​ace@Nucleus map + p300*@Nucleus map → map BCL9:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map
  2. APC|​T1487_pho:​CTBP*|​hm2:​HDAC1_2*@Nucleus map + BCL9:​DVL*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map → map APC|​T1487_pho:​BCL9:​CTBP*|​hm2:​DVL*:​HDAC1_2*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map
  3. APC|​T1487_pho:​BCL9:​CTBP*|​hm2:​DVL*:​HDAC1_2*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map → map APC|​T1487_pho:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map + su_wca1_s_wca3_s405 + CTBP*:​HDAC1_2*:​LEF_TCF*:​WRE*@Nucleus map + DVL*:​JUN|​pho|​pho@Nucleus map
  4. BCL9:​PYGO*:​_beta_-Catenin*|​ace@Nucleus map + CBP*|​S92_pho@Nucleus map → map BCL9:​CBP*|​S92_pho:​PYGO*:​_beta_-Catenin*|​ace|​ace@Nucleus map
  5. KLF8@Nucleus map + BCL9:​PYGO*:​_beta_-Catenin*|​ace@Nucleus map + p300*@Nucleus map → map BCL9:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map
  6. BCL9:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map → map BCL9:​KLF8|​K67_ace|​K93_ace|​K95_ace:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map
  7. HDAC1_2*:​LEF_TCF*:​TLE*|​ubi:​WRE*@Nucleus map + BCL9:​CBP*|​S92_pho:​DVL*:​JUN|​pho|​pho:​PYGO*:​_beta_-Catenin*|​ace|​ace@Nucleus map → map BCL9:​CBP*|​S92_pho:​DVL*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_emp|​ace|​ace@Nucleus map + HDAC1_2*:​TLE*|​ubi@Nucleus map
  8. BCL9:​KLF8|​K67_ace|​K93_ace|​K95_ace:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map + HDAC1_2*:​LEF_TCF*:​TLE*|​ubi:​WRE*@Nucleus map → map BCL9:​KLF8|​K67_ace|​K93_ace|​K95_ace:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map + HDAC1_2*:​TLE*|​ubi@Nucleus map
  9. KLF4@Nucleus map + BCL9:​PYGO*:​_beta_-Catenin*|​ace@Nucleus map + LEF_TCF*@Nucleus map + CTBP*@Nucleus map + gWRE*@Nucleus map → map BCL9:​CTBP*:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​ace@Nucleus map
  10. BCL9:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map + DVL*:​JUN|​pho|​pho@Nucleus map → map BCL9:​DVL*:​JUN|​pho|​pho:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map
  11. DVL*:​JUN|​pho|​pho@Nucleus map + BCL9:​CBP*|​S92_pho:​PYGO*:​_beta_-Catenin*|​ace|​ace@Nucleus map → map BCL9:​CBP*|​S92_pho:​DVL*:​JUN|​pho|​pho:​PYGO*:​_beta_-Catenin*|​ace|​ace@Nucleus map
  12. BCL9@Nucleus map + _beta_-Catenin*|​ace@Nucleus map + PYGO*@Nucleus map → map BCL9:​PYGO*:​_beta_-Catenin*|​ace@Nucleus map
  13. HDAC1_2*:​LEF_TCF*:​TLE*|​ubi:​WRE*@Nucleus map + BCL9:​DVL*:​JUN|​pho|​pho:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map → map BCL9:​DVL*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map + HDAC1_2*:​TLE*|​ubi@Nucleus map
  14. BCL9:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map + SMAD1|​pho@Nucleus map → map BCL9:​PYGO*:​SMAD1|​pho:​TCF4:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map
As Catalyser:
  1. gCyclinD*@Nucleus map → map rCyclinD*@Nucleus map
  2. gAXIN1@Nucleus map → map rAXIN1@Nucleus map
  3. gMMP9@Nucleus map → map rMMP9@Nucleus map
  4. gGenes under control of _br_CBP-mediated transcription*@Nucleus map → map rRNA@Nucleus map
  5. gTCF4@Nucleus map → map rTCF4@Nucleus map
  6. gRAD6B*@Nucleus map → map rRAD6B*@Nucleus map
  7. gBCL9@Nucleus map → map rBCL9@Nucleus map
  8. gMIR372@Nucleus map → map arMIR372@Nucleus map
  9. gMIR373@Nucleus map → map arMIR373@Nucleus map
  10. gIRS2@Nucleus map → map rIRS2@Nucleus map
  11. gCRIPTO-1*@Nucleus map → map rCRIPTO-1*@Nucleus map
  12. _beta_-Catenin*@Cytoplasm map → map _beta_-Catenin*@Nucleus map
  13. BCL9@Cytoplasm map → map BCL9@Nucleus map
  14. gMYC@Nucleus map → map rMYC@Nucleus map
  15. gGene under control of_br_ P300-mediated transcription*@Nucleus map → map rRNA@Nucleus map