Identifiers
NAME:HDAC1_2*:LEF_TCF*:TLE*:WRE*
References
PMID:11266540
s_wca3_re146( Survival ):
HIPK2 phosphorylates any TCF/LEF
PMID:21285352
s_wca3_re147( Survival ):
Phosphorylated TCF/LEF transcription factor dissociates and is replaced by another unphosphorylated one. For example TCF3 (repressor) is phosphorylated by HIPK2 and will dissociate from the complex and is replaced by TCF1.
su_wca1_s_wca3_re147( Survival ):
Identifiers
NAME:HDAC1_2*:LEF_TCF*:TLE*:WRE*
References
PMID:11266540
s_wca3_re111:( Survival ) PMID:16510874
s_wca3_re147( Survival ):
Phosphorylated TCF/LEF transcription factor dissociates and is replaced by another unphosphorylated one. For example TCF3 (repressor) is phosphorylated by HIPK2 and will dissociate from the complex and is replaced by TCF1.
PMID:21285352
s_wca3_re7( Survival ):
The transcription complex containing P300 initiates transcription of genes that are involved in differentiation.
PMID:20920541
The repressor complex is is by default present on the enhancers of wnt-target genes
PMID:16510874
s_wca3_re40( Survival ):
Not sure if ubiquitination by XIAP is necessary for replacement of TLE by b-catenin upon canonical WNT signaling
PMID:22304967
s_wca3_re125( Survival ):
CBP-mediated transcription effects genes that are involved in stemm cell or progenitor cell maintenance and proliferation
Repressor complex is default present on the enhance of wnt-target genes
s_wca3_re146( Survival ):
HIPK2 phosphorylates any TCF/LEF
su_wca1_s_wca3_re125( Survival ):
su_wca1_s_wca3_re146( Survival ):
Identifiers
NAME:HDAC1_2*:LEF_TCF*:TLE*:WRE*
References
PMID:11266540
s_wca3_re40( Survival ):
Not sure if ubiquitination by XIAP is necessary for replacement of TLE by b-catenin upon canonical WNT signaling
PMID:22304967
s_wca3_re6( Survival ):
PMID:16169192
B-catenin competes with TLE for Lef-1
PMID:15768032
CBP-and P300-mediated transcription different cell fates
PMID:20530697
(phosphorylated) C-JUN can bind to TCF4
PMID:18347071 PMID:16007074