RNA MMP9 map

Identifiers
HUGO:MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
HUGO:MMP9, HGNC:7176, ENTREZ:4318, GENECARDS:GC20P044637??
CLG4B "matrix metalloproteinase 9 (gelatinase B 92kD gelatinase 92kD type IV collagenase)" "matrix metalloproteinase 9 (gelatinase B 92kDa gelatinase 92kDa type IV collagenase)"
HUGO:MMP9 HGNC:7176 ENTREZ:4318 UNIPROT:P14780 GENECARDS:MMP9 REACTOME:59395 KEGG:4318 ATLASONC:MMP9ID41408ch20q11 WIKI:MMP9

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / MATRIX_REGULATION  map
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / ECM  map
 Innate Immunity  map  / TUMOR_GROWTH  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map

References
PMID:19847259
In fibroblasts PTEN inhibit ETS2 expression; and AKT and JNK induce phosphorylqtion of ETS2. MMP9 and CCL3 are the direct targets of this transcription factor.
PMID:11875494
MMPs plays important in the degradation and remodeling of the
extracellular matrix at sites of inflammation. HMOX1 (HO1) mediates IL-10-induced suppression
of MMP9 expression.
PMID:23390297, PMID:22461508
MIF signaling induces angiogenesis probavly via upregulation of MMP9, VEGF expression in macrophages and activates tumor invasion

rMMP9@Nucleus

References
mo_re251:( motility  map ) PMID:27328425 PMID:27572739 PMID:27510662

rMMP9@INNATE_IMMUNE_CELL_Cytosol

References
in_re629( Innate Immunity  map ):
PMID:11875494
HMOX1 (HO1) mediates IL-10-induced suppression
of MMP9 expression.
PMID:23390297, PMID:22461508
MIF signaling induces angiogenesis provavly via upregulation of MMP9, VEGF expression.

Modifications:
In compartment: Cytosol
  1. rMMP9@Cytosol map
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. rMMP9@INNATE_IMMUNE_CELL_Cytosol map
In compartment: Nucleus
  1. rMMP9@Nucleus map
Participates in complexes:
In compartment: Cytosol
  1. MIR320A:​MMP9@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. gMMP9@Cytosol map → map rMMP9@Cytosol map
  2. rMMP9@Cytosol map → map MMP9@Cytosol map
  3. arMIR320A@Cytosol map + rMMP9@Cytosol map → map MIR320A:​MMP9@Cytosol map
  4. MIR320A:​MMP9@Cytosol map → map degraded
  5. gMMP9@Nucleus map → map rMMP9@Nucleus map
  6. rMMP9@Nucleus map → map MMP9@Cytosol map
  7. gMMP9@INNATE_IMMUNE_CELL_Cytosol map → map rMMP9@INNATE_IMMUNE_CELL_Cytosol map
  8. rMMP9@INNATE_IMMUNE_CELL_Cytosol map → map MMP9@INNATE_IMMUNE_CELL_Cytosol map
  9. gMMP9@Nucleus map → map rMMP9@Nucleus map
  10. rMMP9@Nucleus map → map MMP9@Cytosol map
  11. gMMP9@Nucleus map → map rMMP9@Nucleus map
As Catalyser: