Complex BCL9:CBP*:DVL*:JUN:LEF_TCF*:PYGO*:WRE*:_beta_-Catenin*
Complex composition:
- BCL9
- PYGO*
- LEF_TCF*
- WRE*
- _beta_-Catenin*
- CBP*
- DVL*
- JUN
BCL9:CBP*|S92_pho:DVL*:JUN|pho|pho:LEF_TCF*:PYGO*:WRE*:_beta_-Catenin*|K345_emp|ace|ace@Nucleus
Identifiers
NAME:BCL9:CBP*:DVL*:JUN:LEF_TCF*:PYGO*:WRE*:_beta_-Catenin*
References
s_wca3_re12( Survival
):
CBP-and P300-mediated transcription different cell fates
PMID:20530697
s_wca3_re125( Survival
):
CBP-mediated transcription effects genes that are involved in stemm cell or progenitor cell maintenance and proliferation
PMID:20920541
Repressor complex is default present on the enhance of wnt-target genes
PMID:16510874
s_wca3_re159( Survival
):
LEF1 has been identified to be involved in transcription of the MIR371-373 cluster. Only unknown if either P300 or CTBP is involved.
PMID:22020335
s_wca3_re163( Survival
):
Though not known if this transcription is mediated by CBP in the transcripoition complex could be otherwise P300
PMID:23296977
Modifications:
Participates in complexes:
In compartment: Nucleus
- BCL9:CBP*|S92_pho:DVL*:JUN|pho|pho:LEF_TCF*:PYGO*:WRE*:_beta_-Catenin*|K345_emp|ace|ace@Nucleus
Participates in reactions:
As Reactant or Product:- HDAC1_2*:LEF_TCF*:TLE*|ubi:WRE*@Nucleus
+ BCL9:CBP*|S92_pho:DVL*:JUN|pho|pho:PYGO*:_beta_-Catenin*|ace|ace@Nucleus
→
BCL9:CBP*|S92_pho:DVL*:JUN|pho|pho:LEF_TCF*:PYGO*:WRE*:_beta_-Catenin*|K345_emp|ace|ace@Nucleus
+ HDAC1_2*:TLE*|ubi@Nucleus
As Catalyser:- gGenes under control of _br_CBP-mediated transcription*@Nucleus
→
rRNA@Nucleus
- gMIR372@Nucleus
→
arMIR372@Nucleus
- gMIR373@Nucleus
→
arMIR373@Nucleus
- gIRS2@Nucleus
→
rIRS2@Nucleus