Protein FANCE map

Identifiers
Fanconi anemia, complementation group E
HUGO:FANCE, HGNC:3586, ENTREZ:2178, UNIPROT:Q9HB96

Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / FANCONI  map
 Cell Cycle DNA Repair  map  / TLS  map

References
PMID:19686080, PMID:19622404, PMID:18931676
FA core complex regulates REV1 and activated TLS
PMID:22266823

FANCE|​S376_pho|​T346_pho@Nucleus

References
ce_re188( Cell Cycle DNA Repair  map ):
PMID:18931676, PMID:19686080, PMID:17296736
Link between cell cycle and activation of Fanconi pathway

FANCE@Nucleus

References
ce_re188( Cell Cycle DNA Repair  map ):
PMID:18931676, PMID:19686080, PMID:17296736
Link between cell cycle and activation of Fanconi pathway

Modifications:
In compartment: Nucleus
  1. FANCE@Nucleus map
  2. FANCE|​S376_pho|​T346_pho@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF@Nucleus map
  2. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@Nucleus map
  3. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​TOP3A@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. FANCC@Nucleus map + FANCE|​S376_pho|​T346_pho@Nucleus map + FANCF@Nucleus map → map FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF@Nucleus map
  2. FANCA|​pho:​FANCG|​S7_pho@Nucleus map + FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF@Nucleus map + FAAP24*:​FANCM@Nucleus map + FAAP100*:​FANCB:​FANCL@Nucleus map + BLM@Nucleus map + HES1@Nucleus map + FAAP20*@Nucleus map → map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@Nucleus map
  3. FANCE@Nucleus map → map FANCE|​S376_pho|​T346_pho@Nucleus map
  4. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@Nucleus map + TOP3A@Nucleus map + RPA1:​RPA2:​RPA3@Nucleus map → map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​TOP3A@Nucleus map
As Catalyser:
  1. gFanconi_DNA_st2*@Nucleus map → map gFanconi_DNA_st3*@Nucleus map
  2. FANCD2|​pho@Nucleus map → map FANCD2|​K561_ubi|​pho@Nucleus map
  3. FANCI|​pho@Nucleus map → map FANCI|​K523_ubi|​pho@Nucleus map
  4. gFanconi_DNA_st4*@Nucleus map → map gFanconi_DNA_st5*@Nucleus map
  5. FANCD2@Nucleus map → map FANCD2|​pho@Nucleus map
  6. FANCD2|​K561_ubi|​pho@Nucleus map + MRE11*:​NBS1*|​S343_pho:​RAD50@Nucleus map + ATR|​pho|​active@Nucleus map → map ATR|​pho:​FANCD2|​K561_ubi|​pho:​MRE11*:​NBS1*|​S343_pho:​RAD50@Nucleus map
  7. gTLS_DNA_st1*@Nucleus map → map gTLS_DNA_st2*@Nucleus map