Protein MLH1 map

Identifiers
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
HUGO:MLH1, HGNC:7127, ENTREZ:4292, UNIPROT:P40692

Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / MMR  map
 Cell Cycle DNA Repair  map  / BER  map

References
PMID:20478261, PMID:18157157, PMID:16612326, PMID:15703371, PMID:19847258, PMID:16697054, PMID:16612326, PMID:18406444

Modifications:
In compartment: Nucleus
  1. MLH1@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. MBD4:​MLH1@Nucleus map
  2. MLH1:​MLH3@Nucleus map
  3. MLH1:​PMS1@Nucleus map
  4. MLH1:​PMS2@Nucleus map
  5. FANCJ*:​MLH1:​PMS2@Nucleus map
  6. ERCC1:​MLH1:​PMS2:​XPF*@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. MLH1:​PMS2@Nucleus map + ERCC1:​XPF*@Nucleus map → map ERCC1:​MLH1:​PMS2:​XPF*@Nucleus map
  2. FANCJ*@Nucleus map + MLH1:​PMS2@Nucleus map → map FANCJ*:​MLH1:​PMS2@Nucleus map
  3. MLH3@Nucleus map + MLH1@Nucleus map → map MLH1:​MLH3@Nucleus map
  4. PMS1@Nucleus map + MLH1@Nucleus map → map MLH1:​PMS1@Nucleus map
  5. MLH1@Nucleus map + MBD4@Nucleus map → map MBD4:​MLH1@Nucleus map
  6. MLH1@Nucleus map + PMS2@Nucleus map → map MLH1:​PMS2@Nucleus map
  7. MLH1:​PMS2@Nucleus map → map ce_s834
  8. MLH1:​PMS1@Nucleus map → map ce_s834
  9. MLH1:​MLH3@Nucleus map → map ce_s834
As Catalyser:
  1. G2 phase@Nucleus map → map M phase@Nucleus map
  2. gFanconi_DNA_st3*@Nucleus map → map gFanconi_DNA_st4*@Nucleus map
  3. gMismatched_nucleotide*@Nucleus map → map gMMR_DNA_st2*@Nucleus map
  4. ATR|​pho|​active@Nucleus map + ATRIP@Nucleus map → map ATRIP:​ATR|​pho@Nucleus map
  5. ATM@Nucleus map → map ATM|​S1981_pho|​S367_pho|​S1893_pho|​active@Nucleus map
  6. ATR@Nucleus map → map ATR|​pho|​active@Nucleus map
  7. gDeaminated_alkylated_mismatched_base*@Nucleus map → map gBER_M-glyc_DNA_st2*@Nucleus map + Base@Nucleus map