Gene Mismatched_nucleotide* map

Identifiers
DNA with mismatched nucleotide incorporation
Node_Type:Generic

Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / MMR  map

References
PMID:23892398
PMID:22258607, PMID:22918414, PMID:20478261
PMID:22976800, PMID:22475811, PMID:22237395

gMismatched_nucleotide*@Nucleus

References
ce_re528:( Cell Cycle DNA Repair  map ) PMID:22237395
ce_re26( Cell Cycle DNA Repair  map ):
BER and MMR interaction and G2/M arrest in responce to o6-meG formation:
PMID:14614141
cMyc physically stimulates MSH2 and MLH1 and activates MMR:
PMID:15814658, PMID:12584560
ce_re179:( Cell Cycle DNA Repair  map ) reactionType:is.a

Modifications:
In compartment: Nucleus
  1. gMismatched_nucleotide*@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gMismatched_nucleotide*@Nucleus map → map gDamaged_DNA*@Nucleus map
    2. gMismatched_nucleotide*@Nucleus map → map gMMR_DNA_st2*@Nucleus map
    3. gIntact_DNA*@Nucleus map → map gMismatched_nucleotide*@Nucleus map
    4. gMismatched_nucleotide*@Nucleus map → map gSingle_strand_breaks_SSB*@Nucleus map
    5. Replication error@Nucleus map → map gMismatched_nucleotide*@Nucleus map
    As Catalyser:
    1. MLH1@Nucleus map + MBD4@Nucleus map → map MBD4:​MLH1@Nucleus map