Protein IL2RG map

Identifiers
HUGO:IL2RG

Maps_Modules
MODULE:MACROPHAGE
MODULE:IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS

References
PMID:23124025, PMID:20856220
In human monocytes, IL-4 mediates its effect through the
type I IL-4R, composed of the IL-4R????and common gamma-chain (IL-2R??);
And, probably through type II IL-4Ris composed of the
IL-4Ra chain and IL-13Ra1

IL2RG@Membrane

Identifiers

Maps_Modules

References

Modifications:
In compartment: Membrane
  1. IL2RG@Membrane map
Participates in complexes:
In compartment: Membrane
  1. IL2RG:​IL4R@Membrane map
  2. IL2RG:​IL4:​IL4R:​JAK1|​pho:​JAK2:​JAK3@Membrane map
Participates in reactions:
As Reactant or Product:
  1. IL2RG@Membrane map + IL4R@Membrane map → map IL2RG:​IL4R@Membrane map
  2. IL4@default map + IL2RG:​IL4R@Membrane map + JAK3@Cytosol map + JAK2@Cytosol map + JAK1@Cytosol map → map IL2RG:​IL4:​IL4R:​JAK1|​pho:​JAK2:​JAK3@Membrane map
As Catalyser:
  1. IRS2@Cytosol map → map IRS2|​pho@Cytosol map
  2. gTIMP3@Cytosol map → map rTIMP3@Cytosol map
  3. STAT3@Cytosol map → map STAT3|​pho|​active@Cytosol map
  4. STAT6@Cytosol map → map STAT6|​pho|​active@Cytosol map