Complex IL2RG:IL4R
Complex composition:
- IL4R
- IL2RG
IL2RG:IL4R@Membrane
Identifiers
NAME:IL2RG:IL4R
Maps_Modules
MODULE:MACROPHAGE
References
PMID:23124025, PMID:20856220
In human monocytes, IL-4 mediates its effect through the
type I IL-4R, composed of the IL-4R????and common gamma-chain (IL-2R??);
And, probably through type II IL-4Ris composed of the
IL-4Ra chain and IL-13Ra1
Modifications:
Participates in complexes:
In compartment: Membrane
- IL2RG:IL4R@Membrane
Participates in reactions:
As Reactant or Product:- IL2RG@Membrane
+ IL4R@Membrane
→
IL2RG:IL4R@Membrane
- IL4@default
+ IL2RG:IL4R@Membrane
+ JAK3@Cytosol
+ JAK2@Cytosol
+ JAK1@Cytosol
→
IL2RG:IL4:IL4R:JAK1|pho:JAK2:JAK3@Membrane
As Catalyser: