Complex NFKB1_p50*:RELA map
Complex composition:

  1. NFKB1_p50* map
  2. RELA map

NFKB1_p50*:​RELA|​pho@Cytosol

Identifiers
NAME:NFKB1_p50*:RELA

Maps_Modules
MODULE:MACROPHAGE

References
PMID: 19171876
NFkB signaling via RELA:p50 heterodimer provides
expression of proinflamatory cytokines and realisation
of M1 phenotype of macrophages.
PMID:12193701, PMID:11830590
CD40 expression is upregulated by STAT1 downstream of INFG
and NF-kB downstream of TNF.

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. NFKB1_p50*:​RELA|​pho@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. NFKB1_p50*:​NFKBIA|​pho:​RELA|​pho@Cytosol map → map NFKB1_p50*:​RELA|​pho@Cytosol map + NFKBIA|​pho@Cytosol map
  2. RELA@Cytosol map + NFKB1_p50*@Cytosol map → map NFKB1_p50*:​RELA|​pho@Cytosol map
  3. NFKB1_p50*:​RELA|​pho@Cytosol map + NFKBIA@Cytosol map → map NFKB1_p50*:​NFKBIA:​RELA@Cytosol map
  4. NFKB1_p50*:​RELA|​pho@Cytosol map → map M1 phenotype of macrophages@Cytosol map
As Catalyser:
  1. gTNF@Cytosol map → map rTNF@Cytosol map
  2. gIL13RA2@Cytosol map → map rIL13RA2@Cytosol map
  3. gABCB1@Cytosol map → map rABCB1@Cytosol map
  4. gIL1B@Cytosol map → map rIL1B@Cytosol map
  5. gCD40@Cytosol map → map rCD40@Cytosol map
  6. gNFKBIA@Cytosol map → map rNFKBIA@Cytosol map
  7. gPTGS2@Cytosol map → map rPTGS2@Cytosol map
  8. gIL12p40*@Cytosol map → map rIL12p40*@Cytosol map
  9. gIL8*@Cytosol map → map rIL8*@Cytosol map
  10. gIL6@Cytosol map → map rIL6@Cytosol map
  11. gNOS2@Cytosol map → map rNOS2@Cytosol map