Identifiers
HUGO:NOS2

Maps_Modules
MODULE:MACROPHAGE
MODULE:MDSC
MODULE:NO_ROS_PRODUCTION

References
PMID:17476345
NOS2, a heme-containing enzyme
that catalyzes the synthesis of NO and citrulline from l???Arg, is
expressed by various cells of the immune system, and its activa-
tion is considered a hallmark of classically activated macrophages
(also known as M1 macrophages), a macrophage subset that pro-
duces proinflammatory cytokines and acts as the effector cell in
the killing of invading pathogens and tumor cells.

Identifiers

Maps_Modules

References

1. rNOS2@Cytosol

1. gNOS2@Cytosol → rNOS2@Cytosol
2. rNOS2@Cytosol → NOS2@Cytosol