Gene PTGS2 map

Identifiers
HUGO:PTGS2

Maps_Modules
MODULE:MACROPHAGE
MODULE:MDSC
MODULE:IMMUNOSTIMULATORY_CYTOKINE_EXPRESSION

References
PMID:23390297
MIF inhitits expression of M1 markers such as PTGS2 (COX2)
PMID: PMID:21670502
KLF4 inhibits PTGS2 (COX2) expression. Probably via prevention of NFkB activaiton.
PMID: 24030977
SCF2 (GM-CSF) promotes the immunosuppressive activity of glioma-infiltrating myeloid cells (MDSC) through upregulation of expression of interleukin-4 receptor-??
ARG1, TGFB, COX2 expression is downregulated in IL4R-/- MDSC (probably via STAT3 and MYC).

gPTGS2@Cytosol

Identifiers

Maps_Modules

References

Modifications:
In compartment: Cytosol
  1. gPTGS2@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gPTGS2@Cytosol map → map rPTGS2@Cytosol map
    As Catalyser: