Protein NFKBIA map

Identifiers
HUGO:NFKBIA

Maps_Modules
MODULE:MACROPHAGE
MODULE:MDSC
MODULE:CORE_SIGNALING_PATHWAYS

References
PMID:10542212
The primary level of control of NFkB heterodimer is through
its interaction with the inhibitorprotein NFKBIA (IkBa). IL10 inhibits
TNF-dependent degradation of NFKBIA.
PMID:17550372, PMID:9743347
IL13 inhibits NF??B activation via prevention of degradation of IkBa
PMID:17485448, PMID:10542212
IL10 Iinhibits IKBa??? ???phosphorylation and proteasomal degradation and prevents activation of downstream??? ???NFkB??? ???signaling.

NFKBIA@Cytosol

Identifiers

Maps_Modules

References

NFKBIA|​pho@Cytosol

Identifiers

Maps_Modules

References

Modifications:
In compartment: Cytosol
  1. NFKBIA@Cytosol map
  2. NFKBIA|​pho@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. NFKB1_p50*:​NFKBIA:​RELA@Cytosol map
  2. NFKB1_p50*:​NFKBIA|​pho:​RELA|​pho@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. NFKBIA|​pho@Cytosol map → map degraded
  2. NFKB1_p50*:​NFKBIA:​RELA@Cytosol map → map NFKB1_p50*:​NFKBIA|​pho:​RELA|​pho@Cytosol map
  3. NFKB1_p50*:​NFKBIA|​pho:​RELA|​pho@Cytosol map → map NFKB1_p50*:​RELA|​pho@Cytosol map + NFKBIA|​pho@Cytosol map
  4. rNFKBIA@Cytosol map → map NFKBIA@Cytosol map
  5. NFKB1_p50*:​RELA|​pho@Cytosol map + NFKBIA@Cytosol map → map NFKB1_p50*:​NFKBIA:​RELA@Cytosol map
As Catalyser: