Reaction transcription re47 map

gIL6@Cytosol map → rIL6@Cytosol map

Reaction regulators:
Catalysis
  1. NFKB1_p50*:​RELA|​pho@Cytosol map
  2. CD14:​IRAK2:​IRAK4:​LY96:​MYD88:​TIRAP:​TLR2/4*@Membrane map
Inhibition
  1. NFKBID@Cytosol map
  2. IRF4@Cytosol map





Identifiers

Maps_Modules

References
PMID:17485448
Inhibition of??? ???NFkB signaling downstream of??? ???ABIN3??? ???
inhibits expression of??? ???IL8,??? ???IL6,??? ???TNF,??? ???IL12
PMID:15749903, PMID:16413922
NFKBID (IkBNS) interacts with NFkB p50 inhibit recrutement NFkB p50/p65 to IL-6 promoter
and inhibit IL6 expression.
PMID:9743347
IL-13 blocks NF-??B-dependent production of IL6
PMID:16243976
IRF4 downregulates expression of TNFa, IL12p40, IL6 probably via inhibition of NF-kB and JNK signaling pathways.