Identifiers
tight junction protein 1
HUGO:TJP1, HGNC:11827, ENTREZ:7082, GENECARDS:GC15M029991, UNIPROT:Q07157??

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence   / EMT_REGULATORS 
 EMT Senescence   / CELL_CELL_ADHESIONS 
 EMT Senescence   / TIGHT_JUNCTIONS 

References
PMID:15558297
The localization of ZO-1 at gap junctions serves in part to resolve reports of ZO-1 expression in non-epithelial cells such as fibroblasts that lack tight junctions

References
em_emtc_emtc_re515( EMT Senescence  ):
PMID:15383321
MTDH is so-called LYRIC
LYRIC colocalizes with ZO1 and Occludin in polarized epithelial cells.
This protein is most likely not involved in the TJ formation as a structural component.
However, it is required for the maturation of the TJ complex
em_emtc_emtc_re538( EMT Senescence  ):
PMID:15980428
PMID:19284610
The associations between Cx43 and ZO-1 and ZO-2 proteins were shown to be under cell-cycle stage-specific control.
Connexin 43 interacts preferentially
with ZO-1 during G0 stage, whereas the interaction with ZO-2 is approximately the same during the various stages
em_emtc_emtc_re648:( EMT Senescence  ) PMID:12808044

1. ZO1*@Cytosol

1. GJA1:​ZO1*@Cytosol
2. LYRIC*:​ZO1*@Cytosol
3. ZO1*:​ZO2_3*@Cytosol
4. Afadin*:​ZO1*@Cytosol
5. GJA3_8*:​ZO1*@Cytosol
6. JAM1_2_3*:​ZO1*@Cytosol

1. rZO1*@Nucleus → ZO1*@Cytosol
2. JAM1_2_3*@Cytosol + ZO1*@Cytosol → JAM1_2_3*:​ZO1*@Cytosol
3. ZO1*@Cytosol + ZO2_3*@Cytosol → ZO1*:​ZO2_3*@Cytosol
4. Afadin*@Cytosol + ZO1*@Cytosol → Afadin*:​ZO1*@Cytosol
5. ZO1*@Cytosol + LYRIC*@Cytosol → LYRIC*:​ZO1*@Cytosol
6. GJA1@Cytosol + ZO1*@Cytosol → GJA1:​ZO1*@Cytosol
7. ZO1_2_3*@Cytosol → ZO1*@Cytosol
8. ZO1_2*@Cytosol → ZO1*@Cytosol
9. ZO1*@Cytosol + GJA3_8*@Cytosol → GJA3_8*:​ZO1*@Cytosol
10. GJA1:​ZO1*@Cytosol → Tight junctions@Neighbouring Cell
11. GJA1:​ZO1*@Cytosol → G0 phase@Cytosol
12. ZO1_3*@Cytosol → ZO1*@Cytosol
13. GJA3_8*:​ZO1*@Cytosol → Gap junctions@Cytosol