Complex GJA3_8*:ZO1* map
Complex composition:

  1. ZO1* map
  2. GJA3_8* map


GJA3_8*:​ZO1*@Cytosol

Identifiers
NAME:GJA3_8*:ZO1*

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CELL_CELL_ADHESIONS  map
 EMT Senescence  map  / GAP_JUNCTIONS  map

References
PMID:12808044
Cx46 (GJA3) and Cx50 (GJA8) interact with ZO-1
PMID:21965293
Cx50 requires an intact PDZ-binding motif and ZO-1 for the formation of functional intercellular channels.
PMID:19439604
ZO-1 formed a clear margin around the large Cx50 plaques instead of being colocalized with the connexin staining.
This finding suggests the involvement of ZO-1 in the composition of tight or adherens junctions around gap-junctional plaques instead of interacting with connexins directly


Modifications:
Participates in complexes:
In compartment: Cytosol
  1. GJA3_8*:​ZO1*@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. ZO1*@Cytosol map + GJA3_8*@Cytosol map map GJA3_8*:​ZO1*@Cytosol map
  2. GJA3_8*:​ZO1*@Cytosol map map Gap junctions@Cytosol map
As Catalyser: