Complex GJA1:ZO1* map
Complex composition:

  1. GJA1 map
  2. ZO1* map

GJA1:​ZO1*@Cytosol

Identifiers
NAME:GJA1:ZO1*

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CELL_CELL_ADHESIONS  map
 EMT Senescence  map  / GAP_JUNCTIONS  map

References
PMID:15980428
PMID:19284610
The associations between Cx43 and ZO-1 and ZO-2 proteins were shown to be under cell-cycle stage-specific control.
Connexin 43 interacts preferentially
with ZO-1 during G0 stage, whereas the interaction with ZO-2 is approximately the same during the various stages
em_emtc_emtc_re656( EMT Senescence  map ):
PMID:15292177
In mouse epithelial cells lacking any ZO-1 expression, there is retarded tight junction formation.
This phenotype was rescued by exogenous expression of ZO-1, but not by ZO-2, suggesting that these proteins are not functionally redundant
em_emtc_emtc_re659( EMT Senescence  map ):
Connexin 43 interacts preferentially with ZO-1 during G0 stage, whereas the interaction with ZO-2 is approximately the same during the various stages

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. GJA1:​ZO1*@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. GJA1@Cytosol map + ZO1*@Cytosol map → map GJA1:​ZO1*@Cytosol map
  2. GJA1:​ZO1*@Cytosol map → map Tight junctions@Neighbouring Cell map
  3. GJA1:​ZO1*@Cytosol map → map G0 phase@Cytosol map
As Catalyser: