References
PMID:12808044
Cx46 (GJA3) and Cx50 (GJA8) interact with ZO-1
PMID:21965293
Cx50 requires an intact PDZ-binding motif and ZO-1 for the formation of functional intercellular channels.
PMID:19439604
ZO-1 formed a clear margin around the large Cx50 plaques instead of being colocalized with the connexin staining.
This finding suggests the involvement of ZO-1 in the composition of tight or adherens junctions around gap-junctional plaques instead of interacting with connexins directly