Protein ZO1_2* map

Identifiers
ZO1_2*
tight junction protein 1
HUGO:TJP1, HGNC:11827, ENTREZ:7082, GENECARDS:GC15M029991, UNIPROT:Q07157??
tight junction protein 2
HUGO:TJP2, HGNC:11828, ENTREZ:9414, GENECARDS:GC09P071766, UNIPROT:Q9UDY2??

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CELL_CELL_ADHESIONS  map
 EMT Senescence  map  / TIGHT_JUNCTIONS  map

ZO1_2*@Cytosol

References
em_emtc_emtc_re654( EMT Senescence  map ):
GJB1 is so-called Connexin 32 or Cx32
PMID:11978007
Cx32 Formation and / or Cx32-Mediated Intercellular Communication Induces Expression and Function of Tight Junctions in Hepatocytic Cell Line
PMID:19284610
Cx32, colocalizes with tight junction proteins ZO-1 and ZO-2 in rat hepatocytes, and small gap junction plaques were found within tight junction strands.
It was suggested that Cx32 can participate in the formation of functional tight junctions and in actin organization.

Modifications:
In compartment: Cytosol
  1. ZO1_2*@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. GJB1:​ZO1_2*@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. Actin cytoskeletal*@Cytosol map + ZO1_2*@Cytosol map → map em_emtc_emtc_s2532
  2. ZO1_2*@Cytosol map → map ZO1*@Cytosol map
  3. ZO1_2*@Cytosol map → map ZO2*@Cytosol map
  4. ZO1_2*@Cytosol map + GJB1@Cytosol map → map GJB1:​ZO1_2*@Cytosol map
  5. GJB1:​ZO1_2*@Cytosol map → map Tight junctions@Neighbouring Cell map
As Catalyser: