Protein COX4I1
Identifiers
cytochrome c oxidase subunit IV isoform 1
HUGO:COX4I1 HGNC:2265 ENTREZ:1327 UNIPROT:P13073
Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
Regulated Cell Death
/ ANTIOXIDANT_RESPONSE
Regulated Cell Death
/ MITOCHONDRIAL_GENES
Regulated Cell Death
/ MITOCHONDRIAL_METABOLISM
Regulated Cell Death
/ OXIDATIVE_PHOSPHOYLATION_AND_TCA_CYCLE
RECON2
Modifications:
Participates in complexes:
In compartment: Mitochondrial inner membrane
- COX4I1:COX5A:COX5B:COX6A*:COX6B*:COX6C:COX7A*:COX7B*:COX7C:COX8*:Cu2+:MT-CO1:MT-CO2:MT-CO3:heme a@Mitochondrial inner membrane
Participates in reactions:
As Reactant or Product:- COX4I1:COX5A:COX5B:COX6A*:COX6B*:COX6C:COX7A*:COX7B*:COX7C:COX8*:Cu2+:MT-CO1:MT-CO2:MT-CO3:heme a@Mitochondrial inner membrane
+ COX4I2@Mitochondrial inner membrane
+ ATP@Mitochondrial Matrix
→
COX4I2:COX5A:COX5B:COX6A*:COX6B*:COX6C:COX7A*:COX7B*:COX7C:COX8*:Cu2+:MT-CO1:MT-CO2:MT-CO3:heme a@Mitochondrial inner membrane
+ ADP@Mitochondrial Matrix
- degraded + MT-CO1@Mitochondrial inner membrane
+ COX5A@Mitochondrial inner membrane
+ COX6A*@Mitochondrial inner membrane
+ COX5B@Mitochondrial inner membrane
+ COX7A*@Mitochondrial inner membrane
+ heme a@Mitochondrial intermembrane space
+ MT-CO3@Mitochondrial inner membrane
+ Cu2+:MT-CO2@Mitochondrial inner membrane
→
COX4I1:COX5A:COX5B:COX6A*:COX6B*:COX6C:COX7A*:COX7B*:COX7C:COX8*:Cu2+:MT-CO1:MT-CO2:MT-CO3:heme a@Mitochondrial inner membrane
As Catalyser:- Cytochrome_C*|ferroheme:cardiolipin@Mitochondrial inner membrane
+ H+@Mitochondrial Matrix
+ O_sub_2_endsub_@Mitochondrial inner membrane
→
Cytochrome_C*|ferriheme:cardiolipin@Mitochondrial inner membrane
+ H+@Mitochondrial intermembrane space
- Cytochrome_C*|ferroheme:cardiolipin@Mitochondrial inner membrane
+ O_sub_2_endsub_@Mitochondrial intermembrane space
→
Cytochrome_C*|ferriheme:cardiolipin@Mitochondrial inner membrane
+ H_sub_2_endsub_O_sub_2_endsub_@Mitochondrial intermembrane space