Complex TNF:TNFRSF1A map
Complex composition:

  1. TNF map
  2. TNFRSF1A map

TNFRSF1A|​hm3:​TNF|​hm3@TNFRSF1 Receptor Complex

Identifiers
NAME:TNF:TNFRSF1A

References
PMID:21920725
rc_re1148( Regulated Cell Death  map ):
PMID:12531547
PMID:11279185
CD95-mediated clustering by ceramide is prerequisite for signaling and death
PMID:26801188
rc_re1279( Regulated Cell Death  map ):
PMID:15310755
DAB2IP would be present at the membrane bound to TNF receptor even in the absence of stimulation
rc_re1557( Regulated Cell Death  map ):
The release of ceramide in small rafts correlates with the fusion of these small membrane domains to large platforms and the trapping of receptor molecules within ceramide-enriched membrane platforms
rc_re1744( Regulated Cell Death  map ):
Stimulation via CD95 or CD40 activates ASM and triggers a translocation of the enzyme onto the cell surface
PMID:8663014
Upon ligation of TNF-??, TNF-R1 recruits FAN through its N-SMase activation domain (NSD) and activates N-SMase
PMID:1330325
TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown.

Modifications:
Participates in complexes:
In compartment: TNFRSF1 Receptor Complex
  1. TNFRSF1A|​hm3:​TNF|​hm3@TNFRSF1 Receptor Complex map
Participates in reactions:
As Reactant or Product:
  1. TNF@Extracellular space map + TNFRSF1A@Cytosol map → map TNFRSF1A|​hm3:​TNF|​hm3@TNFRSF1 Receptor Complex map
As Catalyser:
  1. TRADD@Cytosol map → map TRADD@TNFRSF1 Receptor Complex map
  2. TRAF2@Cytosol map → map TRAF2@TNFRSF1 Receptor Complex map
  3. DAB2IP@Cytosol map → map DAB2IP@TNFRSF1 Receptor Complex map
  4. Ceramide@Cytosol map → map rc_s5993
  5. NSMAF|​pho@Cytosol map → map NSMAF@Cytosol map
  6. NSMAF@Cytosol map + SMPD1@Cytosol map → map NSMAF:​SMPD1@Cytosol map