Identifiers
DAB2 interacting protein
HUGO:DAB2IP HGNC:17294 ENTREZ:153090 UNIPROT:Q5VWQ8

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death   / DEATH_RECEPTOR_PATHWAYS 
 Regulated Cell Death   / TNF_RESPONSE 

References
synonym:AIP1
PMID:15310755
AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death   / DEATH_RECEPTOR_PATHWAYS 
 Regulated Cell Death   / TNF_RESPONSE 

References
rc_re1279( Regulated Cell Death  ):
PMID:15310755
DAB2IP would be present at the membrane bound to TNF receptor even in the absence of stimulation

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death   / DEATH_RECEPTOR_PATHWAYS 
 Regulated Cell Death   / TNF_RESPONSE 

References
rc_re1280( Regulated Cell Death  ):
PMID:17389591
in aortic endothelial cells
rc_re1326( Regulated Cell Death  ):
PMID:18292600
AIP1 recruits phosphatase PP2A to ASK1 in tumor necrosis factor-induced ASK1-JNK activation
PMID:10734135
PMID:8974401
PMID:15310755

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death   / DEATH_RECEPTOR_PATHWAYS 
 Regulated Cell Death   / TNF_RESPONSE 

References
rc_re1279( Regulated Cell Death  ):
PMID:15310755
DAB2IP would be present at the membrane bound to TNF receptor even in the absence of stimulation
rc_re1280( Regulated Cell Death  ):
PMID:17389591
in aortic endothelial cells

1. DAB2IP@Cytosol

1. DAB2IP@TNFRSF1 Receptor Complex
2. DAB2IP|​S604_pho@TNFRSF1 Receptor Complex

1. DAB2IP@Cytosol → DAB2IP@TNFRSF1 Receptor Complex
2. DAB2IP@TNFRSF1 Receptor Complex → DAB2IP|​S604_pho@TNFRSF1 Receptor Complex
3. DAB2IP|​S604_pho@TNFRSF1 Receptor Complex + TRAF2@TNFRSF1 Receptor Complex + TRADD@TNFRSF1 Receptor Complex → rc_s4171