Complex NSMAF:SMPD1 map
Complex composition:

  1. SMPD1 map
  2. NSMAF map

NSMAF:​SMPD1@Cytosol

Identifiers
NAME:NSMAF:SMPD1

References
PMID:8663014
rc_re1744( Regulated Cell Death  map ):
PMID:11279185
Stimulation via CD95 or CD40 activates ASM and triggers a translocation of the enzyme onto the cell surface
PMID:12531547
Upon ligation of TNF-??, TNF-R1 recruits FAN through its N-SMase activation domain (NSD) and activates N-SMase
PMID:1330325
TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown.
rc_re1743:( Regulated Cell Death  map ) PMID:24021978

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. NSMAF:​SMPD1@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. NSMAF@Cytosol map + SMPD1@Cytosol map → map NSMAF:​SMPD1@Cytosol map
As Catalyser:
  1. Sphingomyelin@Cytosol map → map Ceramide@Cytosol map