Phenotype MOMP map
MOMP@Mitochondrial inner membrane

References
mitochondrial outer membrane permeabilization
PMID:26801188
Ceramide channels and mitochondrial outer membrane permeability
rc_re8( Regulated Cell Death  map ):
in Ba/F3 cells, stable expression of the C-terminal cleavage product of BECN1 sensitizes cells to IL3-deprivation induced apoptosis
in vitro, incubation of isolated mitochondria with recombinant BECN1 C-terminal cleavage product triggers release of Omi/HtrA2 and cytochrome c
PMID:11832478
in vitro CASP2 unlike CASP8 induce release of CYCS , DIABLO and AIF form purified mitochondria from Hela cellsPMID: PMID:23242420
calpain-mediated Bax and Atg5 cleavage resulted in the collapse of the mitochondrial membrane potential and cytochrome c release
rc_re1:( Regulated Cell Death  map ) hierarchical:post-MOMP
rc_re2( Regulated Cell Death  map ):
hierarchical:post-MOMP
PMID:14532003
PMID:10929711
PMID:12660240
in Hela upn taxol treatment
rc_re3( Regulated Cell Death  map ):
PMID:11803371
rc_re4( Regulated Cell Death  map ):
PMID:8879205
release of AIF is blocked by BCL2 overexpression
but data supporting direct involvment of MOMP not found in the literature
rc_re5( Regulated Cell Death  map ):
PMID:9892620
PMID:10318956
PMID:12611882
rc_re6( Regulated Cell Death  map ):
PMID:9508780
rc_re9( Regulated Cell Death  map ):
PMID:9894606
in Jurkat
rc_re670:( Regulated Cell Death  map ) PMID:15029247
rc_re1225:( Regulated Cell Death  map ) PMID:11452314
rc_re1871( Regulated Cell Death  map ):
PMID:21179058
PMID:23846383

MOMP@Mitochondria

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_NON_CANONICAL  map

References
MOMP=mitochondrial outer membrane permeabilisation.
PMID:20709625
s_wnc2_re17:( Survival  map ) PMID:21738214

Modifications:
In compartment: Mitochondria
  1. MOMP@Mitochondria map
In compartment: Mitochondrial inner membrane
  1. MOMP@Mitochondrial inner membrane map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. (ANT*:​CK*:​HK*:​PPID:​TSPO:​VDAC*)|​active@Mitochondrial inner membrane map → map MOMP@Mitochondrial inner membrane map
    2. MOMP@Mitochondrial inner membrane map → map ROS production@Mitochondrial inner membrane map
    3. Mitochondria outer~membrane integrity@Mitochondrial inner membrane map → map MOMP@Mitochondrial inner membrane map
    4. su_wnc1_s_wnc2_s54 → map MOMP@Mitochondria map
    5. MOMP@Mitochondria map → map Apoptosis@Mitochondria map
    6. MOMP@Mitochondria map → map Necroptosis@Mitochondria map
    7. BAD|​pho|​pho@Mitochondria map → map MOMP@Mitochondria map
    As Catalyser:
    1. Cytochrome_C*|​ferroheme@Mitochondrial intermembrane space map → map Cytochrome_C*|​ferroheme@Cytosol map
    2. ENDOG@Mitochondrial inner membrane map → map ENDOG@Cytosol map
    3. PINK1@Mitochondrial Matrix map → map PINK1@Mitochondrial Matrix map
    4. DIABLO@Mitochondrial intermembrane space map → map DIABLO@Cytosol map
    5. HTRA2@Mitochondrial intermembrane space map → map HTRA2@Cytosol map
    6. cleaved~AIFM1*@Mitochondrial intermembrane space map → map cleaved~AIFM1*@Cytosol map
    7. Caspase9*@Mitochondrial intermembrane space map → map Caspase9*@Cytosol map
    8. Caspase3_cl_uncl*@Mitochondrial inner membrane map → map Caspase3_cl_uncl*@Cytosol map
    9. SEPT4@Mitochondrial intermembrane space map → map SEPT4@Cytosol map
    10. Caspase2*@Mitochondrial intermembrane space map → map Caspase2*@Cytosol map
    11. AK2@Mitochondrial inner membrane map → map AK2@Cytosol map