Protein Caspase2* map

Identifiers
caspase 2, apoptosis-related cysteine peptidase
HUGO:CASP2 HGNC:1503 ENTREZ:835 UNIPROT:P42575

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DEPENDANCE_RECEPTORS  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

Caspase2*@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DEPENDANCE_RECEPTORS  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

References
rc_re1725:( Regulated Cell Death  map ) PMID:10764727

Caspase2*@Mitochondrial intermembrane space

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DEPENDANCE_RECEPTORS  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

References
rc_re7( Regulated Cell Death  map ):
hierarchical:post-MOMP
PMID:9892620

Caspase2*@Nucleus

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DEPENDANCE_RECEPTORS  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

References
rc_re1401:( Regulated Cell Death  map ) PMID:19203584

Caspase2*|​S122_pho@Nucleus

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DEPENDANCE_RECEPTORS  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

References
rc_re1401:( Regulated Cell Death  map ) PMID:19203584
rc_re1402( Regulated Cell Death  map ):
PMID:19203584
involvment of CRADD is doubtful

Modifications:
In compartment: Cytosol
  1. Caspase2*@Cytosol map
In compartment: Mitochondrial intermembrane space
  1. Caspase2*@Mitochondrial intermembrane space map
In compartment: Nucleus
  1. Caspase2*@Nucleus map
  2. Caspase2*|​S122_pho@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. Caspase2*@Cytosol map → map cleaved~Caspase2*@Cytosol map
    2. Caspase2*@Nucleus map → map Caspase2*|​S122_pho@Nucleus map
    3. Caspase2*|​S122_pho@Nucleus map → map cleaved~Caspase2*@Nucleus map
    4. Caspase2*@Cytosol map → map cleaved Caspase2*@Cytosol map
    5. Caspase2*@Mitochondrial intermembrane space map → map Caspase2*@Cytosol map
    As Catalyser: