Phenotype Mitochondria outer~membrane integrity map
Mitochondria outer~membrane integrity@Mitochondrial inner membrane

References
rc_re8( Regulated Cell Death  map ):
in Ba/F3 cells, stable expression of the C-terminal cleavage product of BECN1 sensitizes cells to IL3-deprivation induced apoptosis
in vitro, incubation of isolated mitochondria with recombinant BECN1 C-terminal cleavage product triggers release of Omi/HtrA2 and cytochrome c
PMID:11832478
in vitro CASP2 unlike CASP8 induce release of CYCS , DIABLO and AIF form purified mitochondria from Hela cellsPMID: PMID:23242420
calpain-mediated Bax and Atg5 cleavage resulted in the collapse of the mitochondrial membrane potential and cytochrome c release


Modifications:
In compartment: Mitochondrial inner membrane
  1. Mitochondria outer~membrane integrity@Mitochondrial inner membrane map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. Mitochondria outer~membrane integrity@Mitochondrial inner membrane map map MOMP@Mitochondrial inner membrane map
    As Catalyser: