Protein HTRA2 map

Identifiers
HtrA serine peptidase 2
HUGO:HTRA2 HGNC:14348 ENTREZ:27429 UNIPROT:O43464

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

References
uniprot:O43464
PMID:23070005

HTRA2@Mitochondrial intermembrane space

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

References
rc_re3( Regulated Cell Death  map ):
hierarchical:post-MOMP
PMID:11803371
rc_re653:( Regulated Cell Death  map ) PMID:15371414

HTRA2@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

References
rc_re3( Regulated Cell Death  map ):
hierarchical:post-MOMP
PMID:11803371
rc_re661:( Regulated Cell Death  map ) PMID:15781261
rc_re665( Regulated Cell Death  map ):
PMID:11583623
PMID:12835328
PMID:12815069
rc_re1234( Regulated Cell Death  map ):
PMID:20125124
by HTRA2
PMID:10521396
by CASP8
PMID:19935698
by CASP2

Modifications:
In compartment: Cytosol
  1. HTRA2@Cytosol map
In compartment: Mitochondrial intermembrane space
  1. HTRA2@Mitochondrial intermembrane space map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. HTRA2@Mitochondrial intermembrane space map → map HTRA2@Cytosol map
    As Catalyser:
    1. RIPK1@TNFRSF1 Receptor Complex map → map cleaved~RIPK1*@TNFRSF1 Receptor Complex map
    2. HAX1@Mitochondrial intermembrane space map → map cleaved~HAX1*@Mitochondrial intermembrane space map
    3. BIRC6@Cytosol map → map cleaved~BIRC6@Cytosol map
    4. XIAP|​S87_unk@Cytosol map → map CAPN2:​Ca2+_@Cytosol map