Protein p85* map

Identifiers
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
HUGO:PIK3R1 HGNC:8979 ENTREZ:5295 UNIPROT:P27986 GENECARDS:PIK3R1 REACTOME:61192 KEGG:5295 ATLASONC:PIK3R1ID41717ch5q13 WIKI:PIK3R1
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
HUGO:PIK3R2 HGNC:8980 ENTREZ:5296 UNIPROT:O00459 GENECARDS:PIK3R2 REACTOME:61194 KEGG:5296 ATLASONC:GC_PIK3R2 WIKI:PIK3R2
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
HUGO:PIK3R3 HGNC:8981 ENTREZ:8503 UNIPROT:Q92569 GENECARDS:PIK3R3 REACTOME:61182 KEGG:8503 ATLASONC:GC_PIK3R3 WIKI:PIK3R3

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / HEDGEHOG  map
 Survival  map  / PI3K_AKT_MTOR  map
 RECON2  map

References
PMID:16847462
PMID:19568798
PMID:12040186

Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. p110*:​p85*@Cytoplasm map
In compartment: Cytosol
  1. p110*:​p85*@Cytosol map
  2. C-FES*|​Y713_pho|​Y811_pho|​hm2:​p110*:​p85*@Cytosol map
In compartment: Endosome
  1. GAB1:​GF:​GRB2:​PI3,4,5-P3:​RAS*:​RTK*|​pho|​pho|​hm2:​SOS*:​p110*:​p85*@Endosome map
In compartment: Lipid Raft
  1. RAS*:​p110*:​p85*@Lipid Raft map
  2. GF:​RTK*|​pho|​pho|​hm2:​p110*:​p85*@Lipid Raft map
  3. GAB1|​Y977_pho|​Y989_pho:​GF:​GRB2:​PI3,4,5-P3:​RAS*:​RTK*|​pho|​pho|​hm2:​SOS*:​p110*:​p85*@Lipid Raft map
Participates in reactions:
As Reactant or Product:
  1. p110*:​p85*@Cytoplasm map + GRB2:​SOS*@Cytoplasm map + PI3,4,5-P3@Lipid Raft map + RTK*@Cytoplasm map + GF@default map + RAS*@Cytoplasm map + GAB1|​Y977_pho|​Y989_pho@Cytoplasm map → map GAB1|​Y977_pho|​Y989_pho:​GF:​GRB2:​PI3,4,5-P3:​RAS*:​RTK*|​pho|​pho|​hm2:​SOS*:​p110*:​p85*@Lipid Raft map
  2. GAB1:​GF:​GRB2:​PI3,4,5-P3:​RAS*:​RTK*|​pho|​pho|​hm2:​SOS*:​p110*:​p85*@Endosome map → map Ubiquitination@Cytoplasm map
  3. GAB1|​Y977_pho|​Y989_pho:​GF:​GRB2:​PI3,4,5-P3:​RAS*:​RTK*|​pho|​pho|​hm2:​SOS*:​p110*:​p85*@Lipid Raft map → map GAB1:​GF:​GRB2:​PI3,4,5-P3:​RAS*:​RTK*|​pho|​pho|​hm2:​SOS*:​p110*:​p85*@Endosome map
  4. GF:​RTK*|​pho|​pho|​hm2@Lipid Raft map + p110*:​p85*@Cytoplasm map → map GF:​RTK*|​pho|​pho|​hm2:​p110*:​p85*@Lipid Raft map
  5. p110*:​p85*@Cytoplasm map + RAS*@Cytoplasm map → map RAS*:​p110*:​p85*@Lipid Raft map
  6. C-FES*|​Y713_pho|​Y811_pho|​hm2|​active@Cytosol map + p110*:​p85*@Cytosol map → map C-FES*|​Y713_pho|​Y811_pho|​hm2:​p110*:​p85*@Cytosol map
  7. C-FES*|​Y713_pho|​Y811_pho|​hm2:​p110*:​p85*@Cytosol map → map PI3K AKT MTOR pathway@Cytosol map
As Catalyser:
  1. PtdIns(4,5)-P2@Lipid Raft map → map PI3,4,5-P3@Lipid Raft map