Reaction state_transition su_akt1_s_akt1_re136 map

GAB1:​GF:​GRB2:​PI3,4,5-P3:​RAS*:​RTK*|​pho|​pho|​hm2:​SOS*:​p110*:​p85*@Endosome map → Ubiquitination@Cytoplasm map

Reaction regulators:
Boolean_logic_gate_and
  1. CBL*@Cytoplasm map and UBC4*@Cytoplasm map and E1*@Cytoplasm map
Catalysis
  1. E1*@Cytoplasm map
  2. CBL*@Cytoplasm map
  3. UBC4*@Cytoplasm map


Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:10514377
PMID:17635922