Protein CK2_alpha_* map

Identifiers
casein kinase 2, alpha 1 polypeptide
HUGO:CSNK2A1 HGNC:2457 ENTREZ:1457 UNIPROT:P68400
HUGO:CSNK2A1 HGNC:2457 ENTREZ:1457 UNIPROT:P68400 GENECARDS:CSNK2A1 REACTOME:201673 KEGG:1457 ATLASONC:GC_CSNK2A1 WIKI:CSNK2A1
casein kinase 2 alpha 3 polypeptide
HUGO:CSNK2A3 HGNC:2458 ENTREZ:283106 UNIPROT:Q8NEV1 GENECARDS:CSNK2A3 KEGG:283106 WIKI:CSNK2A3

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CELL_CELL_ADHESIONS  map
 EMT Senescence  map  / ADHERENS_JUNCTIONS  map
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / GLUCOSE_METABOLISM  map
 Regulated Cell Death  map  / MOMP_REGULATION  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map
 Survival  map  / WNT_NON_CANONICAL  map

References
PMID:10671552
PMID:11348595
PMID:17928543
in vitro phosphorylation of Cadherin at S834, 836, 842 significantly enhances the affinity with which beta-catenin binds cadherins.
GSK3B and CSNK2 (casein kinase II) have been shown to phosphorylate these sites in vitro.
PMID:20976471
PMID:20558317

CK2_alpha_*@Cytosol

References
em_emtc_emtc_re1007( EMT Senescence  map ):
PMID:10671552
PMID:11348595
PMID:17928543
in vitro phosphorylation of Cadherin at S834, 836, 842 significantly enhances the affinity with which beta-catenin binds cadherins.
GSK3B and CSNK2 (casein kinase II) have been shown to phosphorylate these sites in vitro.

Modifications:
In compartment: Cytosol
  1. CK2_alpha_*@Cytosol map
Participates in complexes:
In compartment: Cytoplasm
  1. CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*@Cytoplasm map
  2. CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*@Cytoplasm map
  3. CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*@Cytoplasm map
  4. CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*@Cytoplasm map
  5. APC:​CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*@Cytoplasm map
  6. CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*:​CSN1*:​CSN2*:​CSN3*:​CSN4*:​CSN5*:​CSN6*:​CSN7*:​CSN8*:​PKD*:​USP15@Cytoplasm map
  7. CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*:​CSN1*:​CSN2*:​CSN3*:​CSN4*:​CSN5*:​CSN6*:​CSN7*:​CSN8*:​CUL1:​NEDD8:​PKD*:​RAD6*:​RBX1:​SKP*:​USP15:​_beta_TRCP*@Cytoplasm map
  8. AMER1*:​APC|​S1505_pho|​S1501_pho|​S1504_pho|​S1507_pho|​S1503_pho|​S1510_pho:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho:​CK1_alpha_*:​CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*:​CSN1*:​CSN2*:​CSN3*:​CSN4*:​CSN5*:​CSN6*:​CSN7*:​CSN8*:​CUL1:​E1*:​FAF*:​GSK3*:​NEDD8:​PKD*:​PtdIns(4,5)-P2:​RAD6*:​RBX1:​SKP*:​USP15:​_beta_-Catenin*|​S45_pho|​T41_pho|​S37_pho|​S33_pho|​K19_ubi|​K49_ubi:​_beta_TRCP*@Cytoplasm map
In compartment: Cytosol
  1. CK2_alpha_'*:​CK2_alpha_*:​CK_beta_*@Cytosol map
In compartment: Nucleus
  1. CK2_alpha_'*:​CK2_alpha_*:​CK_beta_*@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. AMER1*:​APC|​S1505_pho|​S1501_pho|​S1504_pho|​S1507_pho|​S1503_pho|​S1510_pho:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2:​_beta_-Catenin*|​S45_pho|​T41_pho|​S37_pho|​S33_pho@Cytoplasm map + CUL1:​E1*:​FAF*:​NEDD8:​RAD6*:​RBX1:​SKP*:​_beta_TRCP*@Cytoplasm map + CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*:​CSN1*:​CSN2*:​CSN3*:​CSN4*:​CSN5*:​CSN6*:​CSN7*:​CSN8*:​PKD*:​USP15@Cytoplasm map → map AMER1*:​APC|​S1505_pho|​S1501_pho|​S1504_pho|​S1507_pho|​S1503_pho|​S1510_pho:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho:​CK1_alpha_*:​CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*:​CSN1*:​CSN2*:​CSN3*:​CSN4*:​CSN5*:​CSN6*:​CSN7*:​CSN8*:​CUL1:​E1*:​FAF*:​GSK3*:​NEDD8:​PKD*:​PtdIns(4,5)-P2:​RAD6*:​RBX1:​SKP*:​USP15:​_beta_-Catenin*|​S45_pho|​T41_pho|​S37_pho|​S33_pho|​K19_ubi|​K49_ubi:​_beta_TRCP*@Cytoplasm map
  2. AMER1*:​APC|​S1505_pho|​S1501_pho|​S1504_pho|​S1507_pho|​S1503_pho|​S1510_pho:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho:​CK1_alpha_*:​CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*:​CSN1*:​CSN2*:​CSN3*:​CSN4*:​CSN5*:​CSN6*:​CSN7*:​CSN8*:​CUL1:​E1*:​FAF*:​GSK3*:​NEDD8:​PKD*:​PtdIns(4,5)-P2:​RAD6*:​RBX1:​SKP*:​USP15:​_beta_-Catenin*|​S45_pho|​T41_pho|​S37_pho|​S33_pho|​K19_ubi|​K49_ubi:​_beta_TRCP*@Cytoplasm map → map CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*:​CSN1*:​CSN2*:​CSN3*:​CSN4*:​CSN5*:​CSN6*:​CSN7*:​CSN8*:​CUL1:​NEDD8:​PKD*:​RAD6*:​RBX1:​SKP*:​USP15:​_beta_TRCP*@Cytoplasm map + APC|​S1505_pho|​S1501_ubi|​S1504_pho|​S1507_pho|​S1503_pho|​S1510_ubi:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho@Cytoplasm map + _beta_-Catenin*|​S45_pho|​T41_pho|​S37_pho|​S33_pho|​K19_ubi|​K49_ubi@Cytoplasm map
  3. APC@Cytoplasm map + CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*@Cytoplasm map → map APC:​CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*@Cytoplasm map
  4. Cell cycle pathway@Cytoplasm map → map APC:​CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*@Cytoplasm map
  5. APC@Cytoplasm map → map CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*@Cytoplasm map
  6. CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*@Cytoplasm map → map CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*@Cytoplasm map
As Catalyser:
  1. E-Cadherin*@Cytosol map → map E-Cadherin*|​S_pho@Cytosol map
  2. MDC1@Nucleus map → map MDC1|​Nter-SDT-motifs_pho@Nucleus map
  3. GPI|​hm2@Cytosol map → map GPI|​S185_pho|​hm4@Cytosol map
  4. BID@Cytosol map → map BID|​pho@Cytosol map
  5. DVL*@Cytoplasm map → map DVL*|​pho|​emp|​emp@Cytoplasm map
  6. E-Cadherin*@Cytoplasm map → map E-Cadherin*|​S840_pho|​S853_pho|​S855_pho@Cytoplasm map
  7. APC@Cytoplasm map → map APC|​S2034_pho@Cytoplasm map
  8. AKT1@Cytoplasm map → map AKT1|​pho@Cytoplasm map