Reaction heterodimer_association su_wca1_s_wca1_re47 map

AMER1*:​APC|​S1505_pho|​S1501_pho|​S1504_pho|​S1507_pho|​S1503_pho|​S1510_pho:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2:​_beta_-Catenin*|​S45_pho|​T41_pho|​S37_pho|​S33_pho@Cytoplasm map + CUL1:​E1*:​FAF*:​NEDD8:​RAD6*:​RBX1:​SKP*:​_beta_TRCP*@Cytoplasm map + CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*:​CSN1*:​CSN2*:​CSN3*:​CSN4*:​CSN5*:​CSN6*:​CSN7*:​CSN8*:​PKD*:​USP15@Cytoplasm map → AMER1*:​APC|​S1505_pho|​S1501_pho|​S1504_pho|​S1507_pho|​S1503_pho|​S1510_pho:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho:​CK1_alpha_*:​CK2_alpha_'*:​CK2_alpha_*:​CK2_beta_*:​CSN1*:​CSN2*:​CSN3*:​CSN4*:​CSN5*:​CSN6*:​CSN7*:​CSN8*:​CUL1:​E1*:​FAF*:​GSK3*:​NEDD8:​PKD*:​PtdIns(4,5)-P2:​RAD6*:​RBX1:​SKP*:​USP15:​_beta_-Catenin*|​S45_pho|​T41_pho|​S37_pho|​S33_pho|​K19_ubi|​K49_ubi:​_beta_TRCP*@Cytoplasm map

Reaction regulators:
Catalysis
  1. CUL1:​E1*:​FAF*:​NEDD8:​RAD6*:​RBX1:​SKP*:​_beta_TRCP*@Cytoplasm map


Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map

References
PMID:19576224 PMID:17143292 PMID:10023660 PMID:21411632 PMID:22730322 PMID:22682247
FAF1 enhances poly-ubiquitination of beta-catenin by acting as scaffold protein
Intact destruction complex in the proteosome complex