Protein BARD1 map

Identifiers
BRCA1 associated RING domain 1
HUGO:BARD1, HGNC:952, ENTREZ:580, UNIPROT:Q99728

Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / HR  map
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / MITOCHONDRIAL_GENES  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map

References
PMID:19772495, PMID:16697054, PMID:19847258

BARD1@Mitochondrial Matrix

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / MITOCHONDRIAL_GENES  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map

BARD1@Site of DNA damage

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / MITOCHONDRIAL_GENES  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map

References
rc_re1507:( Regulated Cell Death  map ) influenceDelete: re to reactants

Modifications:
In compartment: Mitochondrial Matrix
  1. BARD1@Mitochondrial Matrix map
In compartment: Nucleus
  1. BARD1@Nucleus map
In compartment: Site of DNA damage
  1. BARD1@Site of DNA damage map
Participates in complexes:
In compartment: Nucleus
  1. BARD1:​BRCA1@Nucleus map
  2. BARD1:​BRCA1:​BRCA2:​BRIT1*:​DSS1*:​FANCD2|​K561_ubi|​pho:​FANCN*:​RAD51:​RAD52:​SFPQ:​XRCC2:​XRCC3@Nucleus map
In compartment: Site of DNA damage
  1. BARD1:​BRCA1:​BRCC3:​FAM175A:​UIMC1@Site of DNA damage map
Participates in reactions:
As Reactant or Product:
  1. BARD1@Nucleus map + BRCA1|​S988_pho|​S1387_pho|​S1423_pho|​S1497_pho|​S1524_pho|​active@Nucleus map → map BARD1:​BRCA1@Nucleus map
  2. RAD51:​XRCC2:​XRCC3@Nucleus map + BARD1:​BRCA1@Nucleus map + RAD52@Nucleus map + BRCA2:​DSS1*@Nucleus map + FANCN*@Nucleus map + FANCD2|​K561_ubi|​pho@Nucleus map + BRIT1*@Nucleus map + SFPQ@Nucleus map → map BARD1:​BRCA1:​BRCA2:​BRIT1*:​DSS1*:​FANCD2|​K561_ubi|​pho:​FANCN*:​RAD51:​RAD52:​SFPQ:​XRCC2:​XRCC3@Nucleus map
  3. rheavy strand transcript*@Mitochondrial Matrix map → map rMT-TT@Mitochondrial Matrix map + rMT-ND5@Mitochondrial Matrix map + BARD1@Mitochondrial Matrix map + PYCARD@Mitochondrial Matrix map + BAX@Mitochondrial Matrix map + rMT-ND4@Mitochondrial Matrix map + rMT-ND4L@Mitochondrial Matrix map + BRCA1@Mitochondrial Matrix map + rMT-ND3@Mitochondrial Matrix map + BIRC5@Mitochondrial Matrix map + rMT-CO3@Mitochondrial Matrix map + rMT-ATP6@Mitochondrial Matrix map + rMT-ATP8@Mitochondrial Matrix map + rMT-TK@Mitochondrial Matrix map + rMT-CO2@Mitochondrial Matrix map + rMT-TD@Mitochondrial Matrix map + rMT-CO1@Mitochondrial Matrix map + rMT-TW@Mitochondrial Matrix map + rMT-ND2@Mitochondrial Matrix map + rMT-TM@Mitochondrial Matrix map + rMT-TI@Mitochondrial Matrix map + rMT-ND1@Mitochondrial Matrix map + rMT-TL1@Mitochondrial Matrix map + rMT-RNR2@Mitochondrial Matrix map + rMT-TV@Mitochondrial Matrix map + rMT-RNR1@Mitochondrial Matrix map + rMT-TF@Mitochondrial Matrix map + rMT-CYB@Mitochondrial Matrix map
  4. BRCA1@Nucleus map + FAM175A@Site of DNA damage map + UIMC1@Site of DNA damage map + BRCC3@Site of DNA damage map + BARD1@Site of DNA damage map → map BARD1:​BRCA1:​BRCC3:​FAM175A:​UIMC1@Site of DNA damage map
  5. BARD1:​BRCA1:​BRCC3:​FAM175A:​UIMC1@Site of DNA damage map → map BRCA1@Site of DNA damage map + UIMC1@Site of DNA damage map + FAM175A@Site of DNA damage map + BRCC3@Site of DNA damage map + BARD1@Site of DNA damage map
As Catalyser:
  1. gHR_DNA_st2*@Nucleus map → map gHR_DNA_st3*@Nucleus map
  2. DNA~damage@Nucleus map + gDNA2@Nucleus map → map DNA~integrity@Nucleus map