Phenotype DNA~damage map
DNA~damage@Nucleus

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DNA_DAMAGE_RESPONSE  map
 Regulated Cell Death  map  / NECROPTOSIS  map
 Regulated Cell Death  map  / PARTHANATOS  map

References
PMID:23208502
rc_re118( Regulated Cell Death  map ):
PMID:18692468
PMID:9926927
rc_re119( Regulated Cell Death  map ):
PMID:12203114
rc_re1128:( Regulated Cell Death  map ) PMID:23030059
rc_re1235( Regulated Cell Death  map ):
PMID:16839881
PMID:23030059

Modifications:
In compartment: Nucleus
  1. DNA~damage@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. hydroxyl@Cytosol map + DNA~integrity@Nucleus map → map DNA~damage@Nucleus map
    2. DNA~damage@Nucleus map + gDNA2@Nucleus map → map DNA~integrity@Nucleus map
    3. cleaved~AIFM1*@Mitochondrial inner membrane map → map DNA~damage@Nucleus map
    4. DNA~damage@Nucleus map → map PARP1 overactivation@Nucleus map
    As Catalyser:
    1. DNA-PK*@Nucleus map → map DNA-PK*|​unk@Nucleus map
    2. p53*@Nucleus map → map p53*|​S15_pho|​active@Nucleus map
    3. gSESN1@Nucleus map → map rSESN1@Nucleus map
    4. gSESN2@Nucleus map → map rSESN2@Nucleus map
    5. gDRAM1@Nucleus map → map rDRAM1@Nucleus map