Complex CUL1:RBX1:SKP1:SKP2:_beta_TRCP* map
Complex composition:

  1. _beta_TRCP* map
  2. SKP1 map
  3. CUL1 map
  4. RBX1 map
  5. SKP2 map


CUL1:​RBX1:​SKP1:​SKP2:​_beta_TRCP*@Nucleus

Identifiers
NAME:CUL1:RBX1:SKP1:SKP2:_beta_TRCP*

Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
 Cell Cycle DNA Repair  map  / G1_S_CHECKPOINT  map
 Cell Cycle DNA Repair  map  / S_PHASE_CHECKPOINT  map
 Cell Cycle DNA Repair  map  / G2_M_CHECKPOINT  map

References
FANCM is phosphorylated by PLK1 and ubiquitinated by beta-TRCP (in the SCF complex) in response to G2/M checkpoint. Phosphorylated FANCM is degraded and FANCONI pathway is inhibited during mitosis.
PMID:19270156, PMID:19686080, PMID:15459660
ce_re195( Cell Cycle DNA Repair  map ):
FANCM is phosphorylated by PLK1 and beta-TRCP in response to G2/M checkpoint. Phosphorylated FANCM is degraded and FANCONI pathway is inhibited during mitosis.
PMID:19270156


Modifications:
Participates in complexes:
In compartment: Nucleus
  1. CUL1:​RBX1:​SKP1:​SKP2:​_beta_TRCP*@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. _beta_TRCP*@Nucleus map + SKP1@Nucleus map + CUL1@Nucleus map + RBX1@Nucleus map + SKP2@Nucleus map map CUL1:​RBX1:​SKP1:​SKP2:​_beta_TRCP*@Nucleus map
As Catalyser:
  1. FANCM|​pho@Nucleus map map degraded
  2. CyclinD*@Nucleus map map degraded
  3. CyclinE*@Nucleus map map degraded
  4. CDC25A@Nucleus map map degraded
  5. CDC25B@Nucleus map map degraded
  6. WEE1|​pho@Nucleus map map degraded
  7. EMI1*|​pho@Nucleus map map degraded