Complex Actinin*:BCAR1:FAK1*:PXN:Talin*:c-SRC* map
Complex composition:

  1. Actinin* map
  2. Talin* map
  3. c-SRC* map
  4. PXN map
  5. FAK1* map
  6. BCAR1 map

Actinin*:​BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​c-SRC*@Cytosol

Identifiers
NAME:Actinin*:BCAR1:FAK1*:PXN:Talin*:c-SRC*

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / ECM  map
 EMT Senescence  map  / CELL_MATRIX_ADHESIONS  map

References
PMID:15688067
Alpha-actinin servers a link between cytoskeletal actin (in stress fibres) and vinculin at the focal contacts.
Phosphorylation of alpha-actinin by FAK1 (PTK2) redues this ability of linking actin to vinculin, thus prevents the maturation of focal contacts.
em_emtc_emtc_re988( EMT Senescence  map ):
Zyxin is an alpha-actinin- and stress-fibre- binding protein that is present in mature contacts

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. Actinin*:​BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​c-SRC*@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​c-SRC*@Cytosol map + Actinin*@Cytosol map + Actin cytoskeletal*@Cytosol map → map Actinin*:​BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​c-SRC*@Cytosol map
  2. Actinin*:​BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​c-SRC*@Cytosol map + ZYX@Cytosol map → map Actinin*:​BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​ZYX:​c-SRC*@Cytosol map
  3. ARP2_3*@Cytosol map + Actinin*:​BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​c-SRC*@Cytosol map → map ARP2_3*:​Actinin*:​BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​c-SRC*@Cytosol map
As Catalyser: