+ Actinin*@Cytosol + Actin cytoskeletal*@Cytosol → Actinin*:BCAR1:FAK1*|Y_pho|pho:PXN|pho:Talin*:c-SRC*@Cytosol References
PMID:15688067
Alpha-actinin servers a link between cytoskeletal actin (in stress fibres) and vinculin at the focal contacts.
Phosphorylation of alpha-actinin by FAK1 (PTK2) redues this ability of linking actin to vinculin, thus prevents the maturation of focal contacts.