Complex BCAR1:FAK1*:PXN:Talin*:c-SRC* map
Complex composition:

  1. c-SRC* map
  2. Talin* map
  3. PXN map
  4. FAK1* map
  5. BCAR1 map

BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​c-SRC*@Cytosol

Identifiers
NAME:BCAR1:FAK1*:PXN:Talin*:c-SRC*

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / ECM  map
 EMT Senescence  map  / CELL_MATRIX_ADHESIONS  map

References
PMID:15688067
The integrin-binding protein talin recruits FAK1 and vinculin to focal contacts.
em_emtc_emtc_re987( EMT Senescence  map ):
Alpha-actinin servers a link between cytoskeletal actin (in stress fibres) and vinculin at the focal contacts.
Phosphorylation of alpha-actinin by FAK1 (PTK2) redues this ability of linking actin to vinculin, thus prevents the maturation of focal contacts.

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​c-SRC*@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. FAK1*|​Y_pho|​pho:​c-SRC*@Cytosol map + BCAR1@Cytosol map + Talin*@Cytosol map + PXN|​pho@Cytosol map + Vinculin*@Cytosol map → map BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​c-SRC*@Cytosol map
  2. BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​c-SRC*@Cytosol map + Actinin*@Cytosol map + Actin cytoskeletal*@Cytosol map → map Actinin*:​BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​c-SRC*@Cytosol map
As Catalyser: