Protein XRCC4 map

Identifiers
X-ray repair complementing defective repair in Chinese hamster cells 4
HUGO:XRCC4, HGNC:12831, ENTREZ:7518, UNIPROT:Q13426

Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / C_NHEJ  map

References
PMID:20691907, PMID:19772495, PMID:19346677, PMID:15703371, PMID:19847258, PMID:16697054, PMID:19473888, PMID:19808869

Modifications:
In compartment: Nucleus
  1. XRCC4@Nucleus map
  2. XRCC4|​hm2@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. LIG4:​PNK*:​XRCC4@Nucleus map
  2. LIG4:​XLF*:​XRCC4|​hm2@Nucleus map
  3. APLF:​Artemis*|​S645_pho|​S385_pho|​S516_pho|​S518_pho:​DNA-PK*|​hm2:​Ku70*:​Ku80*:​LIG4:​PARP3:​XLF*:​XRCC4|​hm2@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. XRCC4@Nucleus map → map XRCC4|​hm2@Nucleus map
  2. XRCC4@Nucleus map + LIG4@Nucleus map + PNK*@Nucleus map → map LIG4:​PNK*:​XRCC4@Nucleus map
  3. Artemis*|​S645_pho|​S385_pho|​S516_pho|​S518_pho|​active@Nucleus map + LIG4:​XLF*:​XRCC4|​hm2@Nucleus map + PARP3@Nucleus map + DNA-PK*|​hm2|​active@Nucleus map + Ku80*@Nucleus map + Ku70*@Nucleus map + APLF@Nucleus map → map APLF:​Artemis*|​S645_pho|​S385_pho|​S516_pho|​S518_pho:​DNA-PK*|​hm2:​Ku70*:​Ku80*:​LIG4:​PARP3:​XLF*:​XRCC4|​hm2@Nucleus map
  4. XRCC4|​hm2@Nucleus map + LIG4@Nucleus map + XLF*@Nucleus map → map LIG4:​XLF*:​XRCC4|​hm2@Nucleus map
As Catalyser:
  1. gC_NHEJ_DNA_st2*@Nucleus map → map gC_NHEJ_DNA_st3*@Nucleus map
  2. gC_NHEJ_DNA_st4*@Nucleus map → map gC_NHEJ_DNA_st5*@Nucleus map