Protein APLF map

Identifiers
aprataxin and PNKP like factor
HUGO:APLF HGNC:28724 ENTREZ:200558 UNIPROT:Q8IW19

Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / C_NHEJ  map

References
APLF and PARP3 in C_NHEJ
PMID:21211721???
PMID:23178593
PMID:18077224???

APLF@Nucleus

References
ce_re85:( Cell Cycle DNA Repair  map ) PMID:9242410

Modifications:
In compartment: Nucleus
  1. APLF@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. APLF:​Artemis*|​S645_pho|​S385_pho|​S516_pho|​S518_pho:​DNA-PK*|​hm2:​Ku70*:​Ku80*:​LIG4:​PARP3:​XLF*:​XRCC4|​hm2@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. Artemis*|​S645_pho|​S385_pho|​S516_pho|​S518_pho|​active@Nucleus map + LIG4:​XLF*:​XRCC4|​hm2@Nucleus map + PARP3@Nucleus map + DNA-PK*|​hm2|​active@Nucleus map + Ku80*@Nucleus map + Ku70*@Nucleus map + APLF@Nucleus map → map APLF:​Artemis*|​S645_pho|​S385_pho|​S516_pho|​S518_pho:​DNA-PK*|​hm2:​Ku70*:​Ku80*:​LIG4:​PARP3:​XLF*:​XRCC4|​hm2@Nucleus map
As Catalyser:
  1. gC_NHEJ_DNA_st4*@Nucleus map → map gC_NHEJ_DNA_st5*@Nucleus map