Protein PNK* map

Identifiers
Polynucleotide kinase 3'-phosphatase
HUGO:PNKP, HGNC:9154, ENTREZ:11284, UNIPROT:Q96T60

Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / C_NHEJ  map
 Cell Cycle DNA Repair  map  / BER  map

References
PMID:20691907
For C_NHEJ
PMID:17638872, PMID:15385968, PMID:12032095
For BER
PMID:11163244, PMID:19546231

PNK*@Nucleus

References
ce_re22( Cell Cycle DNA Repair  map ):
PMID:18398454
PMID:16449207
RECQL5 activates BER via XRCC1 and PARP1
PMID:22973052

Modifications:
In compartment: Nucleus
  1. PNK*@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. LIG4:​PNK*:​XRCC4@Nucleus map
  2. PARP2|​unk|​pho:​PNK*:​POLB:​WRN|​ace:​XRCC1|​pho@Nucleus map
  3. PARP1|​PolyADPribose_unk|​pho:​PNK*:​POLB:​WRN|​ace:​XRCC1|​pho@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. POLB@Nucleus map + XRCC1|​pho@Nucleus map + PARP1|​PolyADPribose_unk|​pho@Nucleus map + WRN|​ace@Nucleus map + PNK*@Nucleus map → map PARP1|​PolyADPribose_unk|​pho:​PNK*:​POLB:​WRN|​ace:​XRCC1|​pho@Nucleus map
  2. XRCC4@Nucleus map + LIG4@Nucleus map + PNK*@Nucleus map → map LIG4:​PNK*:​XRCC4@Nucleus map
  3. PARP2|​unk|​pho@Nucleus map + WRN|​ace@Nucleus map + PNK*@Nucleus map + XRCC1|​pho@Nucleus map + POLB@Nucleus map → map PARP2|​unk|​pho:​PNK*:​POLB:​WRN|​ace:​XRCC1|​pho@Nucleus map
As Catalyser:
  1. gShP_BER_M-glyc_st4_B-glyc_DNA_st4*@Nucleus map + dNTPs@Nucleus map → map gShP_BER_M-glyc_st5_B-glyc_DNA_st5*@Nucleus map
  2. gC_NHEJ_DNA_st2*@Nucleus map → map gC_NHEJ_DNA_st3*@Nucleus map