Protein ALAS1 map

Identifiers
aminolevulinate, delta-, synthase 1
HUGO:ALAS1 HGNC:396 ENTREZ:211 UNIPROT:P13196

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / RCD_GENES  map
 Regulated Cell Death  map  / PORPHYRIN_METABOLISM  map
 RECON2  map

ALAS1@Mitochondrial intermembrane space

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / RCD_GENES  map
 Regulated Cell Death  map  / PORPHYRIN_METABOLISM  map

References
rc_re838:( Regulated Cell Death  map ) reactionType:is.a

ALAS1@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / RCD_GENES  map
 Regulated Cell Death  map  / PORPHYRIN_METABOLISM  map

References
rc_re836( Regulated Cell Death  map ):
PMID:15496594
in QT6 quail fibroblast expressing ectopic human ALAS1, default in ALAS1 mitochondrial targeting, which is reversed by mutations in the heme recognition motif
PMID:15482256
in Hepa mouse hepatoma cells expressing ectopic human ALAS1, default in ALAS1 mitochondrial targeting, which is reversed by mutations in the heme recognition motif

Modifications:
In compartment: Cytosol
  1. ALAS1@Cytosol map
In compartment: Mitochondrial intermembrane space
  1. ALAS1@Mitochondrial intermembrane space map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. ALAS1@Cytosol map + heme@Cytosol map → map rc_s2699
    2. ALAS1@Mitochondrial intermembrane space map → map ALAS*@Mitochondrial intermembrane space map
    3. rALAS1@Nucleus map → map ALAS1@Cytosol map
    4. ALAS1@Cytosol map → map ALAS1@Mitochondrial intermembrane space map
    As Catalyser: