Complex IL10:IL10RA:IL10RB:JAK1:TYK2 map
Complex composition:

  1. IL10 map
  2. IL10RB map
  3. IL10RA map
  4. JAK1 map
  5. TYK2 map

IL10:​IL10RA:​IL10RB:​JAK1|​pho:​TYK2|​pho@Membrane

Identifiers
NAME:IL10:IL10RA:IL10RB:JAK1

Maps_Modules
MODULE:MACROPHAGE

References
PMID:???21115385, PMID:7543512
???The binding of IL-10 to its receptor activates two members of the Janus kinase family: Jak1 (associated with the IL-1OR1 and
Tyk2 (associated with the IL-10R2)
IL-10 treatment of monocytes results in the tyrosine phosphorylation of tyk2 and Jakl

IL10:​IL10RA|​Y446_pho|​Y496_pho:​IL10RB:​JAK1|​pho:​TYK2|​pho@Membrane

Identifiers
NAME:IL10:IL10RA:IL10RB:JAK1

Maps_Modules
MODULE:MACROPHAGE

References
PMID:???21115385, PMID:7543512
???The binding of IL-10 to its receptor activates JAK1

Modifications:
Participates in complexes:
In compartment: Membrane
  1. IL10:​IL10RA:​IL10RB:​JAK1|​pho:​TYK2|​pho@Membrane map
  2. IL10:​IL10RA|​Y446_pho|​Y496_pho:​IL10RB:​JAK1|​pho:​TYK2|​pho@Membrane map
Participates in reactions:
As Reactant or Product:
  1. IL10:​IL10RA:​IL10RB@Membrane map + JAK1@Membrane map + TYK2@Membrane map → map IL10:​IL10RA:​IL10RB:​JAK1|​pho:​TYK2|​pho@Membrane map
  2. IL10:​IL10RA:​IL10RB:​JAK1|​pho:​TYK2|​pho@Membrane map → map IL10:​IL10RA|​Y446_pho|​Y496_pho:​IL10RB:​JAK1|​pho:​TYK2|​pho@Membrane map
As Catalyser:
  1. STAT3@Cytosol map → map STAT3|​pho|​active@Cytosol map