Identifiers

Maps_Modules

References
PMID:???21115385, PMID:7543512
???The binding of IL-10 to its receptor activates JAK1
Two tyrosines??? (???Tyr??? ???446??? ???and Tyr??? ???496???) ???of IL-10RA
are phosphorylated by the JAK1,??? ???to which
the transcription factor STAT3??? ???binds via its SH2??? ???domain
and in turn becomes itself phosphorylated