Protein APC8* map

Identifiers
cell division cycle 23 homolog (S. cerevisiae)
HUGO:CDC23, HGNC:1724, ENTREZ:8697, UNIPROT:Q9UJX2
cell division cycle 23
"CDC23 (cell division cycle 23 yeast homolog)" "cell division cycle 23 homolog (S. cerevisiae)"
HUGO:CDC23 HGNC:1724 ENTREZ:8697 UNIPROT:Q9UJX2 GENECARDS:CDC23 REACTOME:86758 KEGG:8697 ATLASONC:GC_CDC23 WIKI:CDC23

Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
 Cell Cycle DNA Repair  map  / M_CC_PHASE  map
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / GLUCOSE_METABOLISM  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map

References
PMID:18590585, PMID:17303408, PMID:17660363, PMID:7575488, PMID:15279786

Modifications:
In compartment: Nucleus
  1. APC8*@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*@Nucleus map
  2. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​CDC20@Nucleus map
  3. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​E-Cadherin*@Nucleus map
  4. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​E-Cadherin*|​pho@Nucleus map
  5. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​CDC20|​pho:​CyclinA1*@Nucleus map
  6. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​BUB1|​pho:​BUB3:​BUBR1*:​CDC20:​MAD1*|​pho:​MAD2*@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. E-Cadherin*@Nucleus map + APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*@Nucleus map → map APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​E-Cadherin*@Nucleus map
  2. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*@Nucleus map + CDC20@Nucleus map → map APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​CDC20@Nucleus map
  3. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​E-Cadherin*@Nucleus map → map APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​E-Cadherin*|​pho@Nucleus map
  4. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​E-Cadherin*|​pho@Nucleus map → map APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​E-Cadherin*@Nucleus map
  5. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​CDC20@Nucleus map → map APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​CDC20|​pho:​CyclinA1*@Nucleus map
  6. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​CDC20|​pho:​CyclinA1*@Nucleus map → map APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​CDC20@Nucleus map
  7. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​E-Cadherin*@Nucleus map → map E-Cadherin*@Nucleus map + APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*@Nucleus map
  8. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​CDC20@Nucleus map → map APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*@Nucleus map + CDC20@Nucleus map
  9. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​CDC20@Nucleus map + MAD2*@Nucleus map + BUBR1*@Nucleus map + BUB3@Nucleus map + MAD1*|​pho@Nucleus map + BUB1|​pho@Nucleus map → map APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​BUB1|​pho:​BUB3:​BUBR1*:​CDC20:​MAD1*|​pho:​MAD2*@Nucleus map
  10. APC1*@Nucleus map + APC2*@Nucleus map + APC3*@Nucleus map + APC4*@Nucleus map + APC5*@Nucleus map + APC6*@Nucleus map + APC7*@Nucleus map + APC8*@Nucleus map + APC10*@Nucleus map + APC11*@Nucleus map + APC12*@Nucleus map → map APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*@Nucleus map
  11. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​BUB1|​pho:​BUB3:​BUBR1*:​CDC20:​MAD1*|​pho:​MAD2*@Nucleus map → map APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​CDC20@Nucleus map + BUB3@Nucleus map + BUBR1*@Nucleus map + MAD2*@Nucleus map + MAD1*|​pho@Nucleus map + BUB1|​pho@Nucleus map
  12. APC1*:​APC10*:​APC11*:​APC12*:​APC2*:​APC3*:​APC4*:​APC5*:​APC6*:​APC7*:​APC8*:​E-Cadherin*@Nucleus map → map M phase exit@Nucleus map
As Catalyser:
  1. M phase@Nucleus map → map G1 phase@Nucleus map
  2. CyclinA1*@Nucleus map → map degraded
  3. CyclinB1*@Nucleus map → map degraded
  4. CDC25A@Nucleus map → map degraded
  5. Securin*|​S165_pho@Nucleus map → map degraded
  6. Securin*:​Separin*@Nucleus map → map Securin*@Nucleus map + Separin*@Nucleus map
  7. Separin*@Nucleus map + Securin*@Nucleus map → map Securin*:​Separin*@Nucleus map
  8. SCC1*@Nucleus map + STAG*@Nucleus map + SMC3@Nucleus map + SMC1*@Nucleus map → map SCC1*:​SMC1*:​SMC3:​STAG*@Nucleus map
  9. SCC1*:​SMC1*:​SMC3:​STAG*@Nucleus map → map STAG*@Nucleus map + SCC1*@Nucleus map + SMC3@Nucleus map + SMC1*@Nucleus map