Complex APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:BUB1:BUB3:BUBR1*:CDC20:MAD1*:MAD2* 
Complex composition:
- CDC20
- MAD2*
- BUB3
- BUBR1*
- MAD1*
- BUB1
- APC4*
- APC7*
- APC8*
- APC12*
- APC5*
- APC2*
- APC6*
- APC3*
- APC1*
- APC10*
- APC11*
APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:BUB1|pho:BUB3:BUBR1*:CDC20:MAD1*|pho:MAD2*@Nucleus
Identifiers
NAME:APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:BUB1:BUB3:BUBR1*:CDC20:MAD1*:MAD2*
References
ce_re216( Cell Cycle DNA Repair ):
By CDC20/APC complex:
M to G1 transition
By Mitotic checkpoint complex:
Spindle checkpoint
PARP3 activated spindle checkpoint
PMID:21270334
Tankyrase activated spindle checkpoint
PMID:23197039
ce_re385:( Cell Cycle DNA Repair ) Separin is inhibited by Securin
Modifications:
Participates in complexes:
In compartment: Nucleus
- APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:BUB1|pho:BUB3:BUBR1*:CDC20:MAD1*|pho:MAD2*@Nucleus
Participates in reactions:
As Reactant or Product:- APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:CDC20@Nucleus + MAD2*@Nucleus + BUBR1*@Nucleus + BUB3@Nucleus + MAD1*|pho@Nucleus + BUB1|pho@Nucleus → APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:BUB1|pho:BUB3:BUBR1*:CDC20:MAD1*|pho:MAD2*@Nucleus
- APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:BUB1|pho:BUB3:BUBR1*:CDC20:MAD1*|pho:MAD2*@Nucleus → APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:CDC20@Nucleus + BUB3@Nucleus + BUBR1*@Nucleus + MAD2*@Nucleus + MAD1*|pho@Nucleus + BUB1|pho@Nucleus
As Catalyser:- M phase@Nucleus → G1 phase@Nucleus
- Separin*@Nucleus + Securin*@Nucleus → Securin*:Separin*@Nucleus
- SCC1*@Nucleus + STAG*@Nucleus + SMC3@Nucleus + SMC1*@Nucleus → SCC1*:SMC1*:SMC3:STAG*@Nucleus