Identifiers
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
HUGO:ATP5G1 HGNC:841 ENTREZ:516 UNIPROT:P05496
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
HUGO:ATP5G2 HGNC:842 ENTREZ:517 UNIPROT:Q06055
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
HUGO:ATP5G3 HGNC:843 ENTREZ:518 UNIPROT:P48201
Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
Regulated Cell Death / MITOCHONDRIAL_GENES
Regulated Cell Death / MITOCHONDRIAL_METABOLISM
Regulated Cell Death / OXIDATIVE_PHOSPHOYLATION_AND_TCA_CYCLE
RECON2
Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
Regulated Cell Death / MITOCHONDRIAL_GENES
Regulated Cell Death / MITOCHONDRIAL_METABOLISM
Regulated Cell Death / OXIDATIVE_PHOSPHOYLATION_AND_TCA_CYCLE
References
rc_re898:( Regulated Cell Death ) reactionType:is.a
rc_re979( Regulated Cell Death ):
PMID:11410595
ATPAF1 role in assembly of mitochondrial ATP synthase inferred from yeast, on the basis that ATPAF1 interacts with ATP5B (Y2H) and complements the yeast mutant
similar function suggested for ATPAF2
PMID:14701807
in vitro, human ATPAF2 functions as a protein chaperone
PMID:14757859
a mutation found in gene ATPAF2 from a patient with mitochondrial encephalomyopathies supports the role of ATPAF2 as an ATPase assembly gene
PMID:18953340
TMEM70 is involved in mitochondrial ATP synthase biogenesis
→ Oxidative Phosphorylation@Mitochondrial inner membrane
→ ATP5G*@Mitochondrial inner membrane
+ ATP5B@Mitochondrial inner membrane + ATP5G*@Mitochondrial inner membrane + ATP5C1@Mitochondrial inner membrane + MT-ATP6@Mitochondrial inner membrane + MT-ATP8@Mitochondrial inner membrane → ATP5A1:ATP5B:ATP5C1:ATP5D:ATP5E:ATP5F1:ATP5G*:ATP5H:ATP5I:ATP5J:ATP5J2:ATP5L:ATP5O:ATP5S:MT-ATP6:MT-ATP8@Mitochondrial inner membrane