Complex ATP5A1:ATP5B:ATP5C1:ATP5D:ATP5E:ATP5F1:ATP5G*:ATP5H:ATP5I:ATP5J:ATP5J2:ATP5L:ATP5O:ATP5S:MT-ATP6:MT-ATP8
Complex composition:
- MT-ATP6
- MT-ATP8
- ATP5A1
- ATP5B
- ATP5C1
- ATP5D
- ATP5E
- ATP5O
- ATP5F1
- ATP5G*
- ATP5H
- ATP5I
- ATP5J
- ATP5J2
- ATP5L
- ATP5S
ATP5A1:ATP5B:ATP5C1:ATP5D:ATP5E:ATP5F1:ATP5G*:ATP5H:ATP5I:ATP5J:ATP5J2:ATP5L:ATP5O:ATP5S:MT-ATP6:MT-ATP8@Mitochondrial inner membrane
Identifiers
NAME:ATP5A1:ATP5B:ATP5C1:ATP5D:ATP5E:ATP5F1:ATP5G*:ATP5H:ATP5I:ATP5J:ATP5J2:ATP5L:ATP5O:ATP5S:MT-ATP6:MT-ATP8
Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
Regulated Cell Death
/ MITOCHONDRIAL_GENES
Regulated Cell Death
/ MITOCHONDRIAL_METABOLISM
Regulated Cell Death
/ OXIDATIVE_PHOSPHOYLATION_AND_TCA_CYCLE
References
stoichiometry:FALSE
PMID:12110673
purification of human mitochondrial ATP synthase
PMID:11744738
ATP5SL
rc_re979( Regulated Cell Death
):
PMID:11410595
ATPAF1 role in assembly of mitochondrial ATP synthase inferred from yeast, on the basis that ATPAF1 interacts with ATP5B (Y2H) and complements the yeast mutant
similar function suggested for ATPAF2
PMID:14701807
in vitro, human ATPAF2 functions as a protein chaperone
PMID:14757859
a mutation found in gene ATPAF2 from a patient with mitochondrial encephalomyopathies supports the role of ATPAF2 as an ATPase assembly gene
PMID:18953340
TMEM70 is involved in mitochondrial ATP synthase biogenesis
rc_re981( Regulated Cell Death
):
PMID:10838049
review
rc_re1991:( Regulated Cell Death
) PMID:22841746
Modifications:
Participates in complexes:
In compartment: Mitochondrial inner membrane
- ATP5A1:ATP5B:ATP5C1:ATP5D:ATP5E:ATP5F1:ATP5G*:ATP5H:ATP5I:ATP5J:ATP5J2:ATP5L:ATP5O:ATP5S:MT-ATP6:MT-ATP8@Mitochondrial inner membrane
Participates in reactions:
As Reactant or Product:- ATP5A1:ATP5B:ATP5C1:ATP5D:ATP5E:ATP5F1:ATP5G*:ATP5H:ATP5I:ATP5J:ATP5J2:ATP5L:ATP5O:ATP5S:MT-ATP6:MT-ATP8@Mitochondrial inner membrane
→
Oxidative Phosphorylation@Mitochondrial inner membrane
- degraded + ATP5A1@Mitochondrial inner membrane
+ ATP5B@Mitochondrial inner membrane
+ ATP5G*@Mitochondrial inner membrane
+ ATP5C1@Mitochondrial inner membrane
+ MT-ATP6@Mitochondrial inner membrane
+ MT-ATP8@Mitochondrial inner membrane
→
ATP5A1:ATP5B:ATP5C1:ATP5D:ATP5E:ATP5F1:ATP5G*:ATP5H:ATP5I:ATP5J:ATP5J2:ATP5L:ATP5O:ATP5S:MT-ATP6:MT-ATP8@Mitochondrial inner membrane
As Catalyser:- H+@Mitochondrial intermembrane space
+ ADP@Mitochondrial Matrix
→
H+@Mitochondrial Matrix
+ ATP@Mitochondrial Matrix
- H+@Mitochondrial Matrix
+ ATP@Mitochondrial Matrix
→
H+@Mitochondrial intermembrane space
+ ADP@Mitochondrial Matrix