Identifiers
glucokinase (hexokinase 4)
HUGO:GCK HGNC:4195 ENTREZ:2645 UNIPROT:P35557

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death   / APOPTOSIS 
 Regulated Cell Death   / STARVATION_AUTOPHAGY 
 Regulated Cell Death   / GLUCOSE_METABOLISM 
 Regulated Cell Death   / MITOCHONDRIAL_METABOLISM 
 Regulated Cell Death   / MOMP_REGULATION 
 Regulated Cell Death   / NECROPTOSIS 
 RECON2 

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death   / APOPTOSIS 
 Regulated Cell Death   / STARVATION_AUTOPHAGY 
 Regulated Cell Death   / GLUCOSE_METABOLISM 
 Regulated Cell Death   / MITOCHONDRIAL_METABOLISM 
 Regulated Cell Death   / MOMP_REGULATION 
 Regulated Cell Death   / NECROPTOSIS 

References
rc_re245( Regulated Cell Death  ):
PMID:10531306
allosterinc inhibition of HK1 by glucose 6P
PMID:11078441
HK inhibition by long-chain acyl-CoAs
PMID:10760476
PMID:7130182
GCK inhibition by long-chain acyl-CoAs
PMID:12931191
in mouse liver mitochondria GCK activation by phosphorylated BAD within a mitochondrial protein complex
rc_re641( Regulated Cell Death  ):
in mouse liver mitochondria, protein complex purification

1. GCK@Cytosol

1. BAD|​S91_unk:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial inner membrane
2. BAD|​S91_unk|​pho:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial inner membrane

1. BAD|​S91_unk|​active@Cytosol + GCK@Cytosol + WASF1@Cytosol + PRKAC*@Cytosol + PPP1C*@Cytosol → BAD|​S91_unk:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial inner membrane
2. BAD|​S91_unk:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial inner membrane → BAD|​S91_unk|​pho:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial inner membrane
3. BAD|​S91_unk|​pho:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial inner membrane → BAD|​S91_unk:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial inner membrane

1. glucose@Cytosol + ATP@Cytosol → glucose-6P@Cytosol + ADP@Cytosol